More from #PPPreg - now with Isabelle BOUTRON - perspective from clinical trials. Prereg main function to prevent publication bias. Many studies are not published, and this can distort systematic reviews

Now trials involving human subjects required to be posted on a public registry, and results reported within a year. Endorsed by editors of medical journals - this was game- changing.

Registers: allow us to monitor public availability of research results.
V low rates of reporting all results in 1 yr - unethical bcs patients gave time for research & are waiting for results.
This information can be used to put pressure on researchers, institutions, funders.

Shout out to Ben Goldacre and @trialstracker - can really motivate people to report.
Register also allows us to identify and monitor selective reporting of outcomes.
Look at compare-trials.org