Congrats and great job yukowada with your #HRS2021 award presentation!

Our new mechanism of drug-induced arrhythmia with common variants of ion channel gene SCN5A is out in Circulation. iPSC + genome editing + large biobank enabled this work. Mentored by Dan M Roden MD. Teamed up with Quinn Wells Andrew Glazer Giovanni Davogustto VUMCClinPharm. ahajournals.org/doi/abs/10.116…

Excited for the next “worldwide sodium channel seminar” on Jan 25th. One of the best during the pandemic, giving trainees invaluable interaction with experts in this field. Thank you for organizing this Angelika Lampert Hugues Abriel @[email protected] sodiumchannelseminars.org

Excited for tomorrow’s seminar!

Looking forward to the next worldwide sodium channel seminar on Feb 22, by Dr. Indira Raman. Very stimulating. Thank you for organizing this Angelika Lampert Hugues Abriel @[email protected] sodiumchannelseminars.org

Thank you VUMC Reporter for highlighting our work. Very encouraging for early career scientists and trainees.

Our SCN5A dominant negative study is out at Genetics in Medicine! We found widespread dominant negative effects of missense variants which result in increased arrhythmia risk. Matthew O'Neill Ayesha Muhammad @[email protected] Dan M Roden MD authors.elsevier.com/a/1elZO3vlFUyd…

Looking forward to it!

Today 12pm at #HRS2022, presenting our recent work on the novel ion channel compensation identified in iPSC-CMs. Join us at the pavilion Pod2 and scan the QR code for the full presentation!

Congrats Bian for your great work!! It was fun working with such a talented scientist;)

Happy to contribute to great team science with Matthew O'Neill addressing variable penetrance in long QT syndrome.

I am deeply honored to receive this prestigious award at HRS2023. I thank the HRS review committee and judges for their recognition, and am grateful to Dr. Roden for his mentorship.

Our paper is out: In 420 Long QT patients with a rare KCNH2 variant, nonsense variants showed better outcomes than missense variants through haploinsufficiency over dominant negative effects. Our approach will advance interpretation of KCNH2 variants. academic.oup.com/europace/artic…

Thank you, Dr.Crotti Lia Crotti, for the nice editorial to our paper. It was great to say hello at the HRS meeting. academic.oup.com/europace/artic…

Excited to share our recent paper related to both congenital and acquired long QT syndrome. We propose a novel role of KCNQ1 beyond simply generating IKs in the human heart. academic.oup.com/cardiovascres/…