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It's always very interesting to read several papers together on the same or similar topic.

Just saw that our work on the conformations of charge rich IDPs and three other beautiful papers are summarized in this month's IDP Subgroup State Letter. Thanks BPS IDP Subgroup for that!

Perspective by @PappulabWashU and myself on phase separation out in Molecular Cell today. If you wonder why disordered blobs should matter for biochemical function, I suggest you read this. Spoiler: Condensates are not disordered blobs.

Beautiful experimental work from Mrityunjoy (Joy) Kar and simulations from Furqan Dar, which shape our understanding of the phase separation process! Congrats!

This is a story about Game of Pores — how to capture a disordered dragon in a black hole...👇🐉⚫️

Another paper got published today, this time from Tiemei on the endocytosis of coacervates into liposomes! We want to thank our collaborators from the Huck Group, Mesoscopic Physics of Life (MPol) - Weber Group and prof. Hiroaki Suzuki. Read the article below:

Big congrats!

Life isn't perfect, but sunsets at WashU are.

Our review on the intertwined physics of phase separation and chemical reactions is finally available: authors.elsevier.com/a/1fh3U4r0Uny0… (50 days free access) and arxiv.org/abs/2202.13646. We focus on multicomponent systems and summarize current results. Lot’s to do in the future, though!

So happy to have the sweet celebration in the lab and thanks a lot to our lovely lab members. I would also like to give my thanks to Rohit @PappulabWashU and also my PhD advisor Xuhui Huang. This can't be done without your guidance and support.

It's always a great pleasure to work with such wonderful scholars.

Our article on "mesoscale structure-function relationships in mitochondrial transcriptional condensates" is now available in PNAS! Many thanks to the fantastic team of collaborators from the @NCITomMisteli, @PappulabWashU, and Temiakov labs! doi.org/10.1073/pnas.2…

Biomolecular phase separation with LCST is on fire 🔥

For anyone interested in the early work on MD simulations of proteins with a focus on the work by Karplus and colleagues The emergence of protein dynamics simulations: How computational statistical mechanics met biochemistry by Macuglia, Roux & Ciccotti doi.org/10.1140/epjh/s…

Our MRS Bulletin article discussed perspectives in building kinetic network models to study molecular self-assembly! Congratulations to Bojun Liu Yunrui Qiu & Eshani! May thanks to @tiwarylab & the Kulik Group for the invitation to their special issue! rdcu.be/cX7Ao

I attended the 1st-3rd Symposium Biophysics Postgraduate Student Research in Hong Kong from 2014 to 2017 as a PhD student. Today, I felt so privileged to host the 6th one. We're honoured to have yuji sugita deliver the keynote talk. Thanks to all the speakers. A wonderful day!

Using the polarizable AMOEBA forcefields, we investigated the strengths of cation-pi and pi-pi interactions between amino acids. Our findings reveal distinct impacts of the backbone on these interactions in the dilute vs. dense phase of biomolecular phase separation.