Israel: Continuing to crush COVID-19 Since the mid-Jan. peak: 98% fewer cases (now 116 per day) 97% fewer critically ill (now 6 per day) 99% fewer deaths (now 2 per day) Masks outdoors no longer required, and remaining restrictions can and should probably be lifted

Thanks ASBrS for the opportunity to share our work in the Resident/Fellow Discussion Session happening now. #ASBrS21 In press British Journal of Cancer Vasily Giannakeas @WCRInstitute Women's College Hospital

Important paper from Christian Drosten et al, h/t Ⅎ∀ Overdispersion of viral load in sars-2; 1/3 of those with highest VL mild or asymptomatic. B117 higher VL: suggests mechanism for elevated R0 with B117 Paul Chen science.sciencemag.org/content/early/…

Helpful data to include in discussions about contralateral prophylactic #mastectomy (#CPM)... Risk of contralateral #breastcancer according to first breast cancer characteristics among women in the USA, 1992–2016. bit.ly/3qzMumR

This study suggests that tumor size and grade is associated with long-term survival, and patients with larger tumors, lower tumor grades, and progesterone receptor–positive status experienced significant treatment benefit with receipt of tamoxifen therapy. ja.ma/3x2KeZz

In this cohort study, an increased platelet count was associated with an increased risk of cancer for at least 2 years. The results suggest that individuals with unexplained thrombocytosis should be offered screening for several cancers. ja.ma/3fWlbAO

This was an amazing segment with Pauline Chan CTV Health! David W. Lim you were an amazing speaker and advocate for #breastcancer patient care. Thank you!

I know we are *in* a pandemic, but have you asked how we can prevent the *next* one? Hot off the press— our work with *amazing* partners at IEDCR provides some insight on exposure to poultry and potential risks for avian influenza in urban Bangladesh /1 nature.com/articles/s4159…

There's some potentially very positive news coming out of South Africa on limited virulence associated with omicron. If that proves true it'll be absolutely excellent news. I think it's always a good idea to hope for the best and plan for the worst.

“These data suggest that virtually all individuals with existing anti-SARS-CoV-2 CD8+ T-cell responses should recognize the Omicron VOC, and that SARS-CoV-2 has not evolved extensive T-cell escape mutations at this time.” bioRxiv biorxiv.org/content/10.110…

There is a rise in hospitalization (including ICU) due to the Omicron surge, but this is nowhere near what we would have seen with similar numbers of Delta. Mass vaccination & a less virulent variant are helping. Still have to keep a close watch on healthcare capacity...

Research from Women's College Hospital & University of Toronto shows strong association between multiple solid tumors -- including ovarian cancer -- and high platelet count bit.ly/3rl8NiB #MedNews #onctwitter JAMA Network Open

RIP Sir David Cox 😢 An incredible giant whose contributions are inversely related to his modesty. Last time I saw him, he had just turned 94 on which I congratulated him. “Nothing special, it isn’t a prime number”, he replied. I’m glad he lived to 97 which is, indeed, prime.

Celebrating my friend Dr Steven Narod’s new book out today “A Fair Trial: the Foundations of #BreastCancer”showcasing what he’s learned after studying #bcsm over 35 years! Really appreciate the acknowledgment, Steven! #bcsm Women's College Hospital IHPME Institute of Medical Science Women's College Hospital | Research University of Toronto

Bilateral mastectomy reduces risk for contralateral breast cancer, not mortality healio.com/news/hematolog… Healio

Cohort study including 660k+ women with unilateral breast cancer and followed up for 20 years found that bilateral mastectomy was associated with a statistically significant reduction of contralateral breast cancer risk but not breast cancer mortality. ja.ma/46BmJJT

#BreastCancer’s tough choice: To remove, or not to remove, both breasts, by Vasily Giannakeas Steven Narod David W. Lim theglobeandmail.com/opinion/articl… via Globe Opinion @WCHresearch #BRCA1 #BRCA2