Julia Edgar Thanks 🙏 Julia. Not on Pubmed yet - Wiley @AdvSciNews need to speed up 2 early cites, 1 read it, other cited it to claim the exact opposite of what we show 😳 Journal of Physiology (edited @PGreenhaff). Huge 💪 effort by Tanner Stokes, Ph.D. Howard Cen in Stuart Phillips (he/him) & Jim Johnson, PhD labs

Does fat influence insulin section? Jim Johnson, PhD and colleagues⁩ report robust insulin secretion in response to fatty acid stimulus in ~8% of donors, challenging the idea that fat has negligible effects on insulin release. medrxiv.org/content/10.110…

Way to talk in generalities Joe. Not saying there aren't a lot of fucked up things about pharma. That's why we created Costplusdrugs.com. But to ignore that the same industry has saved who knows how many lives is bullshit and you know it. It's also disrespectful to all

Science rests on factual correctness, not on political correctness.

Why weren’t the same people now weirdly obsessing over a shirtless RFK Jr. equally impressed with Fauci running 3 miles a day while being over the age of 80? Because these people don’t actually care about health. Instead it’s all about optics and internet points.

Fascinating developments in weight loss drugs! Eli Lilly's triagonist phase 2 data: Nearly half of participants achieved >25% weight loss, with a quarter surpassing the impressive >30% mark. The bar continues to rise for incretin-based therapies. nejm.org/doi/full/10.10…

Intriguing data showing the rather dramatic effects of Retatrutide on weight loss in obese participants: nejm.org/doi/10.1056/NE… Given the degree of weight loss, it'd be interesting to know how well lean tissue mass is preserved 💪

Great discussion between Dr. Rhonda Patrick and Dr. Chris McGlory on the anabolic potential of omega-3 fatty acids 🐟🏋️ Check it out 👇youtube.com/watch?v=jx6WPB…

Be aware of length biases in single-cell RNA-seq data cell.com/biophysreports…

A mind-blowing paper has come out today in nature In 2016, JC Venter Institute scientists trimmed a bacterial genome to its barest minimum required for life to synthesize what they called a "minimal genome" (science.org/doi/10.1126/sc…). Today, a group of scientists from

Planes, trains, and automobiles: How cells localize their molecules dlvr.it/StJvt3

RNAseq counting tools are not perfect. I simulated 240 GTEx samples to test multiple tools. Below I show the difference between actual and estimated counts for each simulated sample. But, what is causing this? And will it affect differential expression? (1/7) #Bioinformatics

Interesting article that explains a lot of the junk that's spread on social media these days. nature.com/articles/s4156…. A bit of Googling doesn't = a degree; let's defer to the experts when it matters... TLDR version: nature.com/articles/d4159…

New on physical activity/exercise today: 1. Women derive even more protection than men for all-cause and cardiovascular mortality sciencedirect.com/science/articl… JACC Journals 2. It mitigates negative effects of social isolation and loneliness nature.com/articles/s4422… Nature Mental Health

The information theory of aging has not been tested cell.com/cell/abstract/…

RNA deserves its own massive counterpart to the human genome project, researchers argue | Science | AAAS science.org/content/articl…

Huge congratulations to Dr. Everson Nunes for winning the prestigious AJP-Cell Physiology Best Review Paper award at #APS2024! Well-deserved recognition! 🎉🏆 McMaster University Everson Nunes Tanner Stokes, Ph.D. James McKendry, Ph.D. Brad Currier Stuart Phillips (he/him)

Transcriptomics for Clinical and Experimental Biology Research: Hang on a Seq onlinelibrary.wiley.com/doi/10.1002/gg…

Most recent commentary on the implications of GLP-1 based therapies on skeletal muscle health: ahajournals.org/doi/10.1161/CI…. Great to see the attention this important topic is receiving! See also: pubmed.ncbi.nlm.nih.gov/39265590/ and jamanetwork.com/journals/jama/… Stuart Phillips (he/him) Kevin Hall

As the tariffs come into effect, here's a reminder of how they 'work' ... anyone? Anyone?