In our newly published study we show that the proline-rich antimicrobial peptide (PrAMP) Bac5 has a distinct mode of interaction with the ribosome compared to other PrAMPs…academic.oup.com/nar/article/53…

Pacmanvirus isolated from the Lost City hydrothermal field extends the concept of transpoviron beyond the family Mimiviridae #microbiology #virus #viruses The ISME Journal ISME - International Society for Microbial Ecology academic.oup.com/ismej/article/…

New structure of protist ribosome using RAPPL. biorxiv.org/content/10.110…

Promoting ribosomal incorporation of backbone-modifying nonproteinogenic amino acids into nascent peptides by ATP-binding cassette family-F proteins and EF-P academic.oup.com/nar/article/53…

Excited to share our recent work, which addressed a mechanism by which the eukaryotic ribosomes increase the fidelity of mRNA translation than prokaryotic ribosomes through the eukaryote-specific tentacle-like ribosome structure. academic.oup.com/nar/article/53…

The ChimeraX 1.10 release candidate and daily builds can predict small complexes of proteins, nucleic acids and small molecules using Boltz on your Mac, Windows or Linux computer. rbvi.ucsf.edu/chimerax/data/…

With our RTI colleagues Xiaobin Ling and Wenwen Fang, we report cryo-EM structures of enigmatic bacterial RNA nanocages made of long-noncoding ROOL RNAs. Octamers are held by "A-minor staples" and other interactions. Congrats Xiaobin, Dima et al! nature.com/articles/s4158…

Here, we show that bacterial ribosomes—viewed as conserved drug targets—actually vary across species due to extensive sequence variation in their drug-binding residues. This divergence may lead to intrinsic drug resistance in certain bacterial clades: doi.org/10.1016/j.celr…

Cultivation of Methanonezhaarchaeia, the third class of methanogens within the phylum Thermoproteota | bioRxiv biorxiv.org/content/10.110…

New research from CSIR-CCMB reveals that tiny mistakes in protein synthesis might actually help cells survive stress! These "errors" could trigger protective responses and boost adaptability. 📖 Written by Somdatta Karak Read the full article: buff.ly/sw3HvUW

Preprint from our collaboration with the labs of Gerry Wright and Shura Mankin Mankin_Vazquez_Lab identifying the first translation inhibitor binding to the E-site of the bacterial ribosome… researchsquare.com/article/rs-692…

#ResultatScientifique🔎| Quand l’ARN s’invite dans la réparation de l’ADN 🤝 CNRS 🌍 CNRS Occitanie Ouest ✍️ Aline Marnef & Gaëlle Legube 📕 Nature Cell Biology | nature.com/articles/s4155… insb.cnrs.fr/fr/cnrsinfo/qu…

Out Now! Structure of an archaeal ribosome reveals a divergent active site and hibernation factor bit.ly/3UhiSfp #Archaea #RibosomeStructure #PeptidylTransferase

A resource of RNA-binding protein motifs across eukaryotes reveals evolutionary dynamics and gene-regulatory function: nature.com/articles/s4158…

We are excited to share our latest research on Q-modification in precursor-tRNAs, which just got published in Nature Communications. This was an very exciting and fruitful collaboration with FrancescaTuorto in Heidelberg. nature.com/articles/s4146…

Our RAPPL purification of ribosomes and associated material is finally out. I am really proud of this study in collaboration primary with slavica pavlovic djuranovic lab, as well as Marko Jovanovic and Yaser Hashem Labs. This method aims to replace 60 years old purification of ribosomes by

From bacterial virulence to human disease, researchers gathered in Marburg exploring how Ap₄A and other dinucleoside polyphosphates are rewriting the rules of cellulose signaling across life. 🚀 Huge thanks to all speakers, participants, and organizers. onlinelibrary.wiley.com/doi/10.1002/bi…

Seminars by Dr. Dominique Fourmy and Dr. Satoko Yoshizawa (CNRS, ENS Paris-Saclay, Université Paris-Saclay) on new antibiotic susceptibility tests and innovative antimicrobial strategies. Really enjoyed them — fascinating work!

Out Now! Deep learning reveals antibiotics in the archaeal proteome bit.ly/4lpohMM #DeepLearning #ArtificialIntelligence #Antibiotics

We are pleased to share our paper "Structures and mechanisms of U6 snRNA m6A modification by METTL16” Nature Communications doi.org/10.1038/s41467…