🤔Duda clínica habitual 🧵⤵️ 👉que hacer con dapagliflozina en pacientes con IC, si el eGFR⤵️<25ml/min? Mantener o retirar? #ESCcongress

Only one take home message you need to take home from #ESCCongress 🛑Don’t start tx of diabetes with metformin! ✅ start tx with GLPRA or SGLTi 2023 ESC Guidelines of tx of patients with CVD and DM

#ESCCongress European Society of Cardiology EAPCIPresident ESC President Stephan Achenbach chief 🛑 STOP-DAPT3 Trial The aspirin-free strategy compared w the DAPT strategy failed to attest superiority for major bleeding within 1 month after PCI & was associated with a signal suggesting an

🔥 ILUMIEN IV Trial #ESCCongress 🎯OCT-guided vs Angio-guided PCI 🧩 Co-primary EP 🎯Post-PCI MSA ⬆️ w/OCT 🎯2-year TVF ↔️ (p=0.45) 🧩 OCT ⬇️ 🎯Stent thrombosis 🎯Major dissection 🎯Major malapposition Erik Rafflenbeul MIЯVΛƬ #IC ༄ ｡°

First-line Afib ablation should not be offered to all patients with atrial fibrillation and #HFrEF #ESCCongress European Society of Cardiology Wilfried Mullens HFAPresident Gregg Fonarow MD Khalid Minhas, MD FACC

⚠️Outpatient Worsening Among 👥 With HFmrEF/HFpEF #DELIVER Trial 🎯non-fatal worsening HF events 📌🏥 📌urgent 🚑 visits requiring intravenous HF therapies 📌outpatient oral diuretic intensification DELIVER 👇 72%👥 🚫no worsening HF event 13% outpatient oral diuretic

#DÍCTATE-AHF: early initiation of dapagliflozin in AHF🏥 👉 Totality of DICTATE-AHF data supports the early initiation of dapagliflozin in AH to safely facilitate decongestion and GDMT optimization European Society of Cardiology #ESCCongress

ESC Congress 2023 Hot Line Visual Summaries Looking for the ESC Congress Hot Lines in a nutshell? We've put together the key messages from a selection of this year's exciting trials as visual summaries. #ESCCongress escardio.org/Congresses-Eve…

BREAKING #Semaglutide within 3 months of diagnosis of Type 1 Diabetes eliminated insulin after meals in all 10 patients and daily insulin in 7. HbA1C dropped from 11.7% to 5.9%. Provocative & requires further larger long term prospective validation. nejm.org/doi/full/10.10…

The #SGLTi have likely accrued the most indications of any class across biomedicine in recent regulatory history. boehringer-ingelheim.com/fda-approves-j…

Mechanisms for kidney protection with SGLT2i & GLP1RAs #EASD2023

❗️SURMOUNT-4 Maintenance effects of Tirzepatide vs placebo ❗️#EASD2023 🔸great weight loss with percentage weight loss>25% in over half on treatment 🔹expected weight regain off treatment 🔸impressive BP reduction 🔹unusual to see the maintenance then rise in ALT in placebo

Surmount 4 - ‘maintenance’ study of Tirzapetide. ~mean 25% weight loss at 88 weeks in continued arm; i.e. similar in magnitude to Sleeve gastrectomy! Weight regain in the treatment discontinued arm. Some~20% in the discontinued group were able to maintain weight. #EASD2023

Metabolomics predictors of mild CKD. Well done to the investigators. Cool work #EASD2023 ⬇️

This patient was prescribed Entresto (Sacubitril / Valsartan) for heart failure : 1. what's your diagnosis ? 2. what is the mechanisms ?

What a Match!!!! One of the great matches of #hockey played by Indians. Sreejesh is wall. #Paris2024 #Olympics2024Paris

A simple act, a profound impact! A blood donation camp was held at our Ahmedabad office with the Indian Red Cross Society. Grateful to all donors for their life-saving contribution. #TorrentPharma #BloodDonation #GiftOfLife #WorldBloodDonorDay #IndianRedCross

An old drug in a new era of #HeartFailure: Digitoxin in the spotlight after DIGIT-HF. Read a new #Pharmapulse published in #EHJPharmacotherapy 💔🔍 ow.ly/1gmL50X2KcS EHJ-CVP Editor-in-Chief Felice Gragnano Mattia Galli

2025 Update on resistant hypertension in CKD: where do we stand and where do we go? 🔓doi.org/10.1093/ckj/sf…