AI algorithms can now churn out predictions for the 3D shapes of proteins with a precision matching that of painstaking laboratory techniques. The programs, and the blizzard of protein structures they have revealed, are Science’s 2021 #BOTY. fcld.ly/twr28jc

A DNA molecular printer capable of programmable positioning and patterning in two dimensions science.org/doi/10.1126/sc…

Researchers at the Wyss have developed a suite of DNA nanotechnology tools that are specifically engineered to overcome bottlenecks in the development of new therapies, diagnostics, and understanding of molecular structures. #Diagnostics #Therapeutics wyss.harvard.edu/technology/dna…

**शुभकामना, अरनिको** MIT बाट विद्यावारिधी, हार्भड स्नातक, विश्वस्तरका वातावरणविद्। जलवायु परिवर्तनका मुद्दामा नेपालको उत्कृष्ट प्रतिनिधित्व गर्नसक्ने क्षमता, ईमान र लगन। बुवा नेपाली, आमा स्वीस, श्रीमती थाइ भएका डा. पाँडे आँफैमा नमुना 'विश्व नागरिक' हुन्। ललितपुर-३ मा तहल्का होस्!

Congratulations to the Winners of Click Chemistry!!

What an amazing information about eels!

Amazing molecular technology- thermo cycler free PCR from Taekjip Ha lab 👏🏾

Fantastic opportunity to collaborate with Pressé Lab on this project--we are in JACS today! Combining high-throughput single-molecule measurements with Bayesian nonparametric analysis to untangle molecular heterogeneity. Thank you Steve and Shep! pubs.acs.org/doi/10.1021/ja…

कयाैं परिक्षणबाट दशकाैं लगाएर ठूलाे धनराशी खर्चेर कुनै कुरा परिक्षण गर्छ, थप परिक्षण गर्छ, थुप्रैले गरेका परिक्षणहरूका नतिजाहरू मिलेपछि त्यसकाे सत्यता प्रमाणित गर्छ। हामी चाँहि अँ त्याे कुरा त वेद मै थियाे । त्याे कुरा त पूर्वीया दर्शनले उहिल्यै भनेकाे हाे भन्दियाे कुरा खत्तम।

Amazing work! Demonstrating that DNA origami can be folded/unfolded like paper👏🏾

Check out the preprint of our newest work on single-molecule proteomics! biorxiv.org/content/10.110… Here, we use mechanical force to reconstruct the 3D geometry of a natively folded protein complex at the single-molecule level.

Single-molecule 3D reconstruction for structural proteomics--check out our latest work just published in JACS J. Am. Chem. Soc.! pubs.acs.org/doi/10.1021/ja…

Check out the latest work from Wesley Wong Lab in J. Am. Chem. Soc. entitled, "Mapping Single-Molecule Protein Complexes in 3D with DNA Nanoswitch Calipers." #DNA #Nanotechnology pubs.acs.org/doi/10.1021/ja…

So What Does A President Do? biophysics.org/bps-bulletin/s…

Check out our latest work on measuring cell-adhesion with the CFM on Sunday (Exhibit Hall AB at 1:45, 801-Pos/B567), and on structural single-molecule proteomics with nanoswitch calipers on Monday (204AB at 12:35, 958-FlashTalk; Exhibit Hall AB at 1:45, 1601-Pos/B554)

एक आधुनिक ज्ञानवर्धक Interview (अध्यारोबाट_उज्यालोतिर) मा मेरो भनसुन चल्छ भन्ने खालको कुराकानी (video clip) ले पक्कै राम्रो संदेश दिदैन, अझ भनौ लज्जास्पद खालको। Tika Ram Yatri शुभचिंतकको सुझाव🙏

If you want to unfold the same molecule through multiple directions, DNA nanoswitch caliper is the way to go!

Excited to share that I’ve received a Pilot Grant from the Neuroscience Research Priority Area at the University of Kentucky (UK-NRPA). The project aims to advance our molecular understanding of neurodegenerative diseases using cutting-edge single-molecule techniques!

Just published in ACS Central Science—our latest work using the Centrifuge Force Microscope to quantify immune-cell interactions. The new setup combines high-throughput force spectroscopy with multichannel fluorescence for single-cell studies. pubs.acs.org/doi/10.1021/ac…