🆕2022 ACR/EULAR classification criteria ANCA VASCULITIS 🎁 Tabla de diagnóstico diferencial

Here are the key recommendations! Of note, these recommendations include eosinophilic granulomatosis with polyangiitis. Statement 6 is on avacopan and Statement 7 on the use of plasma exchange.

NEW RESEARCH—A post-hoc analysis of patient-reported outcomes from the ADVOCATE trial shows that patients with ANCA-associated #vasculitis who received avacopan had improvements in health-related quality of life and health utility thelancet.com/journals/lanrh…

Happy Tuesday! Check out "Avacopan in Patients With Rapidly Progressive Glomerulonephritis Requiring Dialysis" with Dr. Santoriello from Columbia's Renal Pathology Department as a coauthor kireports.org/article/S2468-…

#ACR23 #ACRambassador Poster to Look Out for 0685: Efficacy and Safety of Avacopan in Patients with ANCA-Associated Vasculitis Receiving Rituximab in a Phase 3 Trial

⭐️Real world data on use of #avacopan presented by Zach Wallace #vasculitis Important observations to inform the practice and management of #AAV

Substudy of the ADVOCATE trial looked at 214 ANCA assoc vasculitis pts treated with #RTX; avacopan Rx showed improved recovery of renal function, faster reduction in albuminuria and lower glucocorticoid toxicity compared to a prednisone taper. bit.ly/3MW9dI3

Avacopan in GPA - non-inferior to prednisone for induction remission - received FDA approval for treatment of severe active GPA in combo with standard therapy and steroids - should be used in newly diagnosed active or relapsing disease @rheumnow #RNL2023 bit.ly/47fBcd9

Avacopan has many benefits in AAV patients. I wish this drug is landing in Latin America soon... Vasculitis Workshop Barcelona #VasculitisBCN2024 #VasculitisBCN2024

Treatment of ANCA associated #vasculitis AAV in 2024 👉🏼#Rituximab standard for remission induction & maintenance 👉🏼Rapid taper glucocorticoid ▶️ similar efficacy 👉🏼#Avacopan allows reduced GC exposure By Prof Bernhard Hellmich #EULAR2024

🫘✅ANCA Vasculitis treatment doi.org/10.1093/ndt/gf… NDT Hans-Joachim Anders

Happy Thursday! Registration is open for ANCA-Vasculitis 2025: Update in Diagnosis and Treatment (March 7, 2025). Feel free to register for our virtual program using the following link: eventleaf.com/Attendee/Atten…

1a/ 🚨📢Hey, #Nephtwitter, #Medtwitter, today we will discuss the real-world evidence of avacopan in ANCA-associated vasculitis (AAV) based on the @KIreports blog 🔗kireportscommunity.org/post/avacopan-…

Renal Recovery for Patients with ANCA Vasculitis and Low eGFR in the ADVOCATE Trial of Avacopan ca. 2023 from KIReports #KidneyWk #Nephpearls 👉 pubmed.ncbi.nlm.nih.gov/37069984/

Real-World Experience With Avacopan in ANCA Vasculitis ca. 2024 from KIReports #KidneyWk #Nephpearls 👉 pubmed.ncbi.nlm.nih.gov/38899183/

Avacopan especially beneficial for: ▫️↑ risk of glucocorticoid-related adverse events ▫️ ↑ burden of cardio-metabolic disease ▫️ ↓ eGFR at presentation In progress: long-term safety and efficacy, role in maintenance and combination strategies. 🔗 doi.org/10.3390/jcm132…

GPA (Granulomatosis with Polyangiitis) Wegeners •Treat with… •Prednisone & Rituximab •Alternative to Rituximab is… •Cyclophosphamide •Long-term steroid use requires… •TMP/SMX for… •PCP prophylaxis •Avacopan is… •C5 inhibitor for GPA and microscopic polyangiitis.

Avacopan 💊 Anti C5a molecule 🎯 New hope for AAV kidney 💦🫵 Rapid taper of steroid by 4 weeks 👍 Can be part of induction and to continue at least one year. 👍 30 mg BD🫵 Miles to go🫸🫷 🫵Have a look on CanVasc consensus recommendation #ACR2024 #ACRAmbassador

Avacopan for ANCA-associated vasculitis with hypoxic pulmonary haemorrhage academic.oup.com/ndt/article/39…

Top ten tips in managing ANCA vasculitis: ▫️Make the diagnosis as early as possible ▫️Induction: Use glucocorticoids + rituximab and/or cyclophosphamide. ▫️Use low-dose glucocorticoid regimen ▫️Use avacopan early ▫️Maintenance: Use rituximab 🔗doi.org/10.1093/ckj/sf…