Congratulations to David Goldberg of Penn NGG and Wanding Zhou’s lab on an excellent update on brain DNA #methylation in #AD and #PART at #ADPD2024. Briefly, the brain epigenome explains variance in tau accumulation and has regional specificity. Preprint coming soon!

It’s early days but exciting times: today at #ADPD2024 Prevail Therapeutics suggest one year #Phase1 evidence for AAV-mediated rise in GRN #FTD progranulin to normal levels from PROCLAIM trial. Thanks to Penn FTD Center team who supported recruitment for this trial!

The #TDP session at #ADPD2024 is a packed house — demonstrating increasing recognition for importance of cross-talk across neurodegenerative diseases.

Thanks to the Remember Me Podcast for continuing to highlight the #FTD research of the Penn FTD Center! In this episode I discuss the overlap of #FTD and #ALS, how we’re trying to break down silos in the field, and the hope we have for emerging treatments podcasts.apple.com/us/podcast/rem…

It’s fantastic to work with such a talented team. The Penn FTD Center celebrated many recent achievements today: new faculty roles, AAN award, first R01 grant, and tenure — go team! David Irwin Jeff Phillips Dr. Lauren Massimo

Join the free workshop "Defining the FTD & ALS Spectrum" on Sept 18 in Amsterdam prior to International Society for Frontotemporal Dementias 2024, including multiple perspectives both within the FTD and ALS communities and beyond to refine biological and clinical concepts of #FTD and/or #ALS. tinyurl.com/FTDALS

Surprise - FTLD-TDP Type C is a dual proteinopathy! Annexin A11 co-accumulates with TDP-43 in all cases of FTLD-TDP Type C. #annexinopathy #FTD #dementia #ADRD #ActaNeuropathologica doi.org/10.1007/s00401…

Happy Thursday! As the end of the week approaches, check out this publication investigating annexin A11 aggregation in FTLD-TDP type C and related neurodegenerative proteinopathies. doi.org/10.1007/s00401… Corey McMillan (he/him/his), David Irwin, Silvia Porta, Vivianna Van Deerlin, Eddie Lee

Welcome to Philly #AAIC2024! With The AFTD, we are hosting a free reception for anyone interested in #FTD research this Tuesday — hope to see you there!

If you are attending the #AAIC2024 join this event. Everyone of the #FTD community is invited!

Check this out! #AAIC2024 #FTD The AFTD

Hey, folks--here for AAIC and wondering where you should eat and drink in Philly? Check out this good blog from Penn FTD Center trainee and local foodie Lasya Sreepada: bit.ly/eatlas-home. And feel free to hit up folks from Penn FTD Center or Penn Memory Center for recs! #AAIC24

Katie Cousins from the Penn FTD Center & Penn Memory Center reports on considerations of diversity in establishing #AD plasma biomarkers. #AAIC2024

Wonderful plenary by Eddie Lee today at #AAIC2024 highlight the importance of microscopic human studies, the environment around us, & the critical importance of inclusion! #AAIC

Important work presented by Dr. Barbara Spencer at #AAIC24: C9orf72 repeat expansions increase risk for secondary motor and cognitive-behavioral symptoms in bvFTD and ALS Corey McMillan (he/him/his) Penn FTD Center

Looking forward to presenting at #AAIC24 tomorrow (July 30th). Visit poster #778 to hear more about our work Corey McMillan (he/him/his) Penn FTD Center Penn Memory Center investigating how a polygenic risk score for executive function correlates with differential rates of cognitive decline! 🧬

This is such a wonderful team from the Penn FTD Center and great week sharing our research at #AAIC2024!

Chris Brown from Penn Memory Center and Corey McMillan (he/him/his) shared his hypothesis-driven #PET and #MRI approach this morning at #AAIC2024 — individualized prediction models win supporting network spread hypothesis of #tau.

The Penn FTD Center is congratulating Astrid P. Ramos-Rolon and Mohammed Saqib as trainees of the Cross-Disciplinary Training in Translational Neuroimaging of ADRD. For more information, click the link in our bio ☝️

Still free registration slots to join us in Amsterdam before International Society for Frontotemporal Dementias: talks on #ALS, #PLS, #PMA, #FTD, #MSP - cognition, behavior, muscle, genes, pathology - we’re trying to figure out how it’s all connected! Supported by MND Association The AFTD Eli Lilly and Company @passagebio Alector