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Today we remember our dear colleague, Shyam Somasundaram, who died suddenly one year today. His loss is still felt acutely by many, professionally and personally. We took a few moments this morning as a lab to share our memories of this incredible scientist and man.

In this study, Saito et al analyse a Japanese 🇯🇵 patient with a type of #oculocutaneous #albinism. They find a variant in their genome coding for SLC24A5 p.G200R. Then, they characterise this variant with a mouse model, which shows pigmentation defects! onlinelibrary.wiley.com/doi/10.1111/pc…

📢 #FreeAccess Review! New therapies such as immune checkpoint blockers have extended survival of #melanoma patients, but they have debilitating side effects. Here, Robinson et al review the role of #eosinophils in treatment response modulation 👇🏽 onlinelibrary.wiley.com/doi/10.1111/pc…

#freeaccess #Artificial #intelligence (AI) applications in #melanoma detection, prognosis, and treatment are rapidly developing. Here, Stiff et al MetroHealth discuss contemporary investigational applications a& challenges of #AI in #melanoma: onlinelibrary.wiley.com/doi/10.1111/pc…

Our #March 2022 issue is out now! Volume 35, Issue 2: onlinelibrary.wiley.com/doi/10.1111/pc… In memoriam: Beatrice Mintz, PhD With contributions by David Adams, Julia Newton-Bishop, Carlos Torres-Cabala, MD, M Valdebran, TJ Knackstedt, T Suzuki, LF Xiang, F Yu, S Gaddameedhi & Robsahm

#OpenAccess #Melanoma has observed a female advantage in incidence, mortality, & overall survival since the 1970s. In this Review, Dakup et al highlight epidemiological evidence of these sex differences & summarize the landscape of their potential origin: onlinelibrary.wiley.com/doi/10.1111/pc…

Excited to see my meeps (melanoma peeps) and get their feedback on new work. Also super excited for my first in person lunch with trainees!

Read this #FreeAccess #Review by Wei Li and collaborators discussing novel insights into #Hermansky–#Pudlak #syndrome (HPS), a condition characterised by defects of multiple tissue-specific lysosome-related organelles: onlinelibrary.wiley.com/doi/10.1111/pc…

Small update this morning on our previously published work in Pigment Cell & Melanoma Research.

Here, Yu et al establish & characterize an immortalized #giant #congenital #melanocytic #nevi cell line. They assess gene expression & driver mutation status, & show this line has a ⬇️ proliferation rate & ⬆️ melanin content than primary melanocytes: onlinelibrary.wiley.com/doi/10.1111/pc…

Oxidative stress is one of the triggering factors for #vitiligo, which leads to #melanocyte destruction in these lesions. Here, Wu et al investigate the role of #ferroptosis in vitiligo & its inhibition in vitro: onlinelibrary.wiley.com/doi/10.1111/pc…

We invite you all to follow ISID2023Tokyo for the latest news on the 1st International Societies for Investigative Dermatology Meeting to be held in Tokyo from 10-13 May 2023. Join us at the “Olympics” of skin science! Visit the website: isid2023.org #ISID2023

Beatrice Mintz (1921–2022) In memoriam We remember Dr Mintz, her charisma and enormous scientific contributions with this piece by Lionel Larue onlinelibrary.wiley.com/doi/10.1111/pc… (Image courtesy of Fox Chase Cancer Center)

Melanomas can vary greatly in how they look. Many show all of the ABCDE features. However, some sub-types of melanoma may have only one or two of the ABCDE features or even none at all.

📢 Our July 2022 issue is out now! With studies by van Geel, Pringle, Barral, Lu, Fabra, Rizos & Szlosarek. Cover image based on "Identification and functional assays of single-nucleotide variants of opsins genes in melanocytic tumors" by Lu et al. onlinelibrary.wiley.com/toc/1755148x/2…

📢 Check out our July issue, now out! Volume 35, Issue 4 With papers by the groups of N. van Geel, J. H. Pringle, D. C. Barral, H. Lu, À. Fabra, P. W. Szlosarek & Helen Rizos! Here: onlinelibrary.wiley.com/toc/1755148x/2…

Speaking soon #SMR2022 really hoping to have some interesting discussion regarding adjuvant therapy trial design in early stage melanoma Society For Melanoma Research