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Useful approach to flatten the molecules commonly obtained in donor-acceptor cyclopropane chemistry - thanks to Gwyndaf Oliver and Simon Kolb @werzlab Universität Freiburg Freiburg Chemistry Institutes for this work now in Angewandte Chemie

Big thanks to Derek Lowe for the thoughtful commentary on our manuscript! Your insights on antifungal research and the challenges we face in drug discovery are invaluable. What the Antifungals Are Really Doing | Science | AAAS science.org/content/blog-p…

Excited to share our latest work in JACS on asymmetric HAT catalysis, with our collaborators Knowles, Houk, and Mayer! Check out how peptide-based catalysts mediate selective radical transformations. Huge congrats to Marcus, Yiran, and the whole team: pubs.acs.org/doi/10.1021/ja…

Now published! Congrats to Wee Boon again! Read the final version at nature.com/articles/s4146…!

Surprise, surprise: Phenothiazine Sulfoxides as Active Photocatalysts! 💡⚗️💡Exciting 🚀collaboration between Oliver Wenger group and Glorius Group published in J. Am. Chem. Soc. : pubs.acs.org/doi/10.1021/ja…

Synthesis of Glycolipid Library Reminiscent of Mycobacterial Cell Wall Motif A and Its Significance by Microscopy (Srinivas Hotha and co-workers) Srinivas Hotha • onlinelibrary.wiley.com/doi/10.1002/an…

We’re excited to share our work that introduces singly N-protected O-vinylhydroxylamines as ring-annulation reagents for the synthesis of azaindolines and azaindoles. Congrats to Zach & Charlotte (Charlotte) and the Enamine (Enamine Ltd 🇺🇦) team! 🔗 chemrxiv.org/engage/chemrxi…

🎉 Big day for our group: our first publication is out! Tom did a fantastic job highlighting current trends & opportunities in peptide catalysis — now published in Chem Catalysis (open access). Huge congrats, Tom! cell.com/chem-catalysis… #PeptideCatalysis #ChemCatalysis

We've designed an RNA-targeted small molecule that reduces toxic 4R tau protein linked to FTDP-17. This orally bioavailable and brain-penetrant compound shows promise in mitigating cellular pathologies and behavioral phenotypes in mouse models. Link here biorxiv.org/content/10.110…

This Alexei Demchenko, PhD (he/him) paper #234 describes a new avenue for the activation of thioglycosides. Halophilic Metal Salts for the Cooperatively Catalyzed Activation of Thioglycosides | The Journal of Organic Chemistry pubs.acs.org/doi/full/10.10…

The First Caspase-3 Chemiluminescent Probe. Appearing today in Bioconjugate Chemistry: pubs.acs.org/doi/full/10.10…

Our new preprint introduces a new approach for controlling the helicity and handedness of polyaromatics using a helical synthon: isobenzofuranophane. We demonstrate the applicability by remotely controlling the handedness and pitch of [5]helicenes. go.shr.lc/44yCyln

Our latest paper is now out in J. Am. Chem. Soc. ! We unveil a new strategy to access elusive free oxoboranes—highly reactive species—via bridged boranoanthracenes and aromatization-driven extrusion. Congratulations to the team! pubs.acs.org/doi/10.1021/ja…

Honored to be named a 2025 Ross M. Brown Investigator! browninstitute.caltech.edu We’re taking on a grand challenge: building stable, neutral allotropes of nitrogen (N₄) as clean, ultra energy-dense fuels. No combustion & emissions. Just on-demand decomposition to pure hot N₂ gas.

New preprint: Ultra-sensitive, sequencing-free detection of #LungCancer via new methylation microarrays. We show >90% sensitivity & specificity from just a blood draw, with therapy monitoring potential at low-cost #LiquidBiopsy #Epigenetics #cfDNA doi.org/10.1101/2025.0…

Great to see this work now available online: Cu(I)-Catalyzed Stereoselective Glycosylation of “Electron-Deficient” Glycals | The Journal of Organic Chemistry pubs.acs.org/doi/10.1021/ac… Well done Mukul Mahanti Dr Natalie Fey N. Walker and C. Sauders Bristol Chemistry TECS and Bristol ChemSynth CDTs

Our work identifying new covalent inhibitors of Staphylococcus aureus serine hydrolyses from fragment libraries is out! great work by @tulsiupadhyay.bsky.social and our many collaborators, including @christianslentz.bsky.social, @mfellnerlab.bsky.social. link.springer.com/article/10.103…

The Stereoselectivity of Neighboring Group-Directed Glycosylation Is Concentration-Dependent | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/ja…

🎊Happy to share two recent papers from the lab：Lanxin’s review on chemical biology tools for anti-fungal strategies doi.org/10.1016/j.cbpa…, and Jeric’s work on characterizing Bifidobacteria Mep on peptidoglycan modification doi.org/10.1039/D5CB00…

Half off all carbohydrates are in the ocean ! These sugars hold tremendous potential as materials, medications and to build better climate models. Exploring marine glycans: structure, function, and the frontier of chemical synthesis - pubs.rsc.org/en/content/art…