Researchers @marcnol Messina Olivier mgötz apply a multiplexed DNA-FISH Hi-M method to dissect the sources of heterogeneity in topologically associating domain (TAD)-like organization during Drosophila embryogenesis. go.nature.com/3Rc3ddC

Congrats Victoria @giacomo_cavalli and all co-authors !!

How do distant DNA loci come into contact to activate genes? Our paper combining live imaging 🔬& polymer physics 🧬 to answer this is out in Science Magazine! We show how chromosome packing & diffusion determine pairwise dynamics & transcription 👉science.org/doi/10.1126/sc… 1/n

2nd part of the transcription and 3D genome organisation session of #futureimaging2023. Olivier MESSINA from CBS in Montpellier on sequential multiplexed imaging mouse cell-type specific chromatin conformation and #TADs. #PhDwork

Happy to share our recent work on extremely long-range (up to 5.1 Mb 😯) #regulation of certain #genes in fly neurons and provides new insights into how they form (short thread below 👇). genesdev.cshlp.org/gca?gca=genesd…

📽️ G&D Tapes 📽️ G&D Author, Marion Solbach Mouginot tells us about their recent study in #genesdev describing how meta-domains control neuronal gene expression. Learn more here: ➡️ bit.ly/45wGi5M #TAD #chromatin #transcription #neuron #drosophila #3Dgenome