🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Congratulations to SantanaCodina lab on your amazing time in the Mancias Lab! We are so lucky to have worked with you over the years on #PancreaticCancer biology and are pumped to see what your #NewPI adventure holds in store! Buen viaje and good luck Naiara!!

Two recent preclinical studies highlight the importance of ferritinophagy in pancreatic cancer, with elevation of a ferritinophagy expression signature also predicting poor prognosis in patients with PDAC: aacrjournals.org/cancerdiscover… and aacrjournals.org/cancerdiscover… #PancSM

Happy to share our latest work now out in @nature. At long last, we resolved the structure of the SHOC2-RAS-PP1C complex and integrated this work with deep mutational scanning to comprehensively evaluate #SHOC2 structure and function. 🧵(1/n) nature.com/articles/s4158…

🚨Job Posting: The Shah Lab & Lyssiotis Lab are looking for a postdoc to study the role of iron, O2, & metabolism in erythropoiesis. Opportunities to learn and employ multiple cutting-edge technologies in 2 ~pretty cool labs 😁 DM with interest.

Thanks to Cancer Discovery for featuring our stories Mancias Lab and Rushika M. Perera on the cover of the September issue!

On the cover!! Thanks Cancer Discovery for featuring work from our lab by Miru Ravichandran and Mancias Lab SantanaCodina lab on the cover !

Robert Hale's determination in Dana-Farber and the Hale Family's incredible generosity help drive Hale Family Center For Pancreatic Cancer Research closer to a cure for pancreatic cancer. forbes.com/video/63128816…

Now online in Cancer Discovery: Targeting UGCG Overcomes Resistance to Lysosomal #Autophagy Inhibition by Vaibhav Jain, David Speicher, Ravi Amaravadi,MD and colleagues The Wistar Institute Penn Medicine - Abramson Cancer Center aacrjournals.org/cancerdiscover…

Latest Wolpin-Nowak lab paper on single cell, in situ protein-based characterization of transcriptional subtypes in pancreatic cancer now out in Cancer Research aacrjournals.org/cancerres/arti…

A cross-country collaboration between former Damon Runyon-Rachleff Innovators Rushika M. Perera and Mancias Lab uncovered another way that #PancreaticCancer evades targeted therapies – and a new potential therapeutic target: bit.ly/3uQwFgd

Pancreatic cancer cells operate a recycling program that would be the envy of any municipality — but the only beneficiaries are the cells themselves. blog.dana-farber.org/insight/2022/1…

Researchers at Dana-Farber and other institutions recently made important discoveries into the recycling system of pancreatic cancer cells, a promising step toward targeted therapies for one of the most challenging cancers. blog.dana-farber.org/insight/2022/1…

We are so inspired by patients like Candace and her experience. With a loving and supportive family and the latest treatments at Dana-Farber, Candace is a source of hope for more patients with pancreatic cancer. blog.dana-farber.org/insight/2023/0…

Our #OpenAccess review on #PancreaticCancer - advances & challenges is now online at Cell Many thanks to Chris Halbrook PascaLab & Lyssiotis Lab for all the hard work & Dr. Jiaying Tan for the opportunity. It’s FREE to read so share widely! cell.com/cell/fulltext/…

WE ARE HIRING! We are looking for a motivated postdoc to work on a fully-funded project studying the role of iron metabolism in drug resistance in pancreatic cancer. 3 weeks left to apply. Please spread the word. au.dk/om/stillinger/… lnkd.in/eNgDM74z

#AACRpan23 Grace Hernandez presenting her poster today - an awesome collaboration with Mancias Lab

The (almost) full program is now online with an amazing lineup of speakers! #AACRPan24 Eileen M O’Reilly Mancias Lab Jash Datta, MD Teresa Zimmers Dr. Andrew Hendifar Tobias Janowitz Wantong Yao Mara Sherman Lab KenOliveLab Andrew Aguirre Channing Der Bryant Lab UNC Erica D. Pratt Michael Goggins

Joseph D. Mancias discussed "Targeting Autophagy in Pancreatic Cancer" in a Rising Star Keynote Lecture during the AACR Special Conference on Advances in Pancreatic Cancer Research. #AACRpan24 Mancias Lab

During the keynote addresses at #AACRpan24, Eileen M. O’Reilly and Joseph D. Mancias discussed how understanding pancreatic cancer’s strengths can help researchers uncover its weaknesses. Learn more on the #AACRBlog: bit.ly/47G1kQ9 Eileen M O’Reilly Mancias Lab

How #autophagy influences the regulation of MHC-I class receptors and regulates #immune evasion of #cancer? A new role for an autophagy receptor IRGQ in this process with a clinical relevance for the development of liver carcinoma in humans and mice 😊😀 sciencedirect.com/science/articl…