
Shaun Mahony
@mahonylab
Studying gene regulation and transcription factor binding specificity with machine learning. Assoc Prof @ Penn State. 🇮🇪
ID: 740044065954275328
http://mahonylab.org/ 07-06-2016 04:53:49
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Check out this preprint showcasing a collaborative project between three CEGR labs (Bai Lab PSU, Shaun Mahony, and Tan lab) studying the sequence features dictating the binding specificity of the FOXA1 pioneer factor in human cancer cells.



Working with scATAC-seq data? My student Yuqi Cheng will present a new tool from our lab, EpiPack, designed specifically for the distinct features across scATAC-seq data batches, that performs integration, reference mapping and new cell type identification #rsgdream2023 #RSGDREAM


Yifei HUANG (Yifei Huang), our dear colleague, Asst Prof Penn State Biology, passed away from cancer in October at the age of 40. We are collecting donations for his daughter's education. All donations are tax-deductible. Penn State Research Please RT. gofund.me/ef82effe


biorxiv.org/content/10.110… Our manuscript characterizing the shortest k-mer sequences unique in humans. We find that they are enriched in neuronal genes and are hotspots for pathogenic variants! Ioannis Mouratidis @MaxwellKonnaris Nikol Chantzi @bigmonty12 and others!

Thrilled to see my Penn State BMB colleague Anton Nekrutenko Anton Nekrutenko 🇺🇦 and colleagues' Galaxy Project paper in Nature Biotechnology. Penn State Eberly College of Science Huck Institutes

Uh-oh!! We're back!! And this time we're taking no prisoners!! The Penn State Bioinorganic Workshop will be held in person again this summer from May 29-June 4 Penn State Eberly College of Science. Check out the website for further information. Always an awesome time and learning experience!!



Check out our latest work in eLife - the journal! This work, led by graduate student James (graduating Sunday) uses a range of techniques, including a new methylation-based method to dissect gene cluster in haploid yeast. doi.org/10.7554/eLife.…

Check out our latest paper in Nature Communications where we develop a methylation-based sequencing assay to capture chromosomal interactions with a viewpoint nature.com/articles/s4146…


Penn State Biology is looking for a Tenure Track Evolutionary Genomicist. We are a welcoming and supportive community - come work with us! Penn State Eberly College of Science Read more here: tinyurl.com/599td3nj #blackinstem #latinxinstem #indigenousinstem #diversityinstem #lgbtSTEM #womeninstem



Excited that we have a paper coming out in Genome Research exploring comparisons of epigenetic landscapes between species to find and better understand gene regulatory elements. genome.cshlp.org/content/early/…

Delighted to have worked on this perspective on the cis-regulatory code with Julia Zeitlinger (@[email protected]), Jason Ernst Lab, Ferhat Ay, Anthony Mathelier, Alejandra Medina-Rivera, Shaun Mahony, Saurabh Sinha arxiv.org/abs/2411.04363. We provide an overview of current progress and some challenges to think about.