Places on Earth that don't look real - thread 🧵 1. Namibia, where the desert meets the ocean

Humbled for moderating a heated session on periop trial designs at AACR , with a great panel: Harpreet Singh, MD Raymond Osarogiagbon, MBBS, FACP Dr. Elizabeth Jaffee Michael Axelson Francesco Pignatti Manju George MVSc PhD Rectal Cancer Survivor Thank you all!

We need more smaller trials to evaluate the other checkpoints and understand whether they’re induced within and across cancer types. This is how we can understand when each combination should be used. Padmanee (Pam) Sharma, MD, PhD Jim Allison PhD AACR #AACR24

The nuances of our analysis discussed here. Pardon the accent! x.com/thelancetoncol…

The Future of Registrational Trials with Multiple Arms: Bernardo Haddock Lobo Goulart will moderate this session at the FDA Oncology-AACR workshop on Trial Designs for Treatment Regimens with Multiple Phases (May 9). Learn more: bit.ly/3weWwmx #AACRSciencePolicy

.U.S. FDA's Bernardo Hoddock Lobo Goulart moderated a session on the Future of Registrational Trials With Multiple Arms. The session starts with a presentation by Minghua Shan of Bayer Pharmaceuticals. @Lobo_Goulart #AACRSciencePolicy

Big call out for patient-centric trials of perioperative therapies today 👇 FDA-AACR Workshop: How Much is Enough? Trial Designs for Treatment Regimens with Multiple Phases - American Association for Cancer Research (AACR) aacr.org/professionals/…

Spread the word! National Black Family Cancer Awareness Week is approaching in June. Let's unite to raise awareness, reduce disparities, and eventually lower the cancer mortality rate within our community. Together, we can make a difference. #BlackFamCan youtu.be/7htK_8u3QqA?si…

Check out the state of immunotherapy in resectable NSCLC: This ASCO Ed Book article includes views from academia & FDA. Good warmup for #ASCO24 Education Session “Integrating Immunotherapy into Early-Stage Lung Cancer" on June 2. 🧵 1/2 ascopubs.org/doi/10.1200/ED… #OCEPublications

2/2 → Ongoing trials of immunotherapy and RT for early stage NSCLC. → Clinical implications of recent advances in immunotherapy for resectable NSCLC. → Current trial designs assessing immunotherapy in resectable NSCLC: challenges, opportunities. Bernardo Haddock Lobo Goulart #ASCO24

Attending #ASCO24? FDA Oncology experts will be speaking ASCO Annual Meeting May 31-June 4 in Chicago. Add these talks to your calendar! fda.gov/about-fda/onco… #OCETalks

Look forward to discussing immunotherapy & trial designs for resectable NSCLC at #ASCO24 Ed session: Integrating Immunotherapy Into Early-Stage Lung Cancer. Join Rafal Dziadziuszko Jamie Chaft and Bernardo Haddock Lobo Goulart to review progress & challenges in this hot topic!

New commentary in #ILCN: Dr. Ke-Neng Chen highlights the importance of avoiding unnecessary treatments and using a multidisciplinary approach in the treatment of NSCLC. bit.ly/4aAgruj #LCSM

Hope to see you tomorrow!

FDA Oncology Center's Dr. Luckson Mathieu will be speaking at Mass General Cancer Center 2024 #CancerEquityColloquium June 14-15. This hybrid event will address the diverse issues that underlie #cancerinequities. tinyurl.com/mryjj68b #OCETalks

Just thinking...I strongly advocate changing the dose selection process to a minimal effective dose (balance efficacy with QOL), but I also think WE NEED A SHIFT IN the AE GRADING SYSTEM to include impact, not just safety. PRO's are invaluable for understanding the patient

Don’t fly with United Airlines. They cancelled 2 flights in a row - same day for the same destination - The second cancellation was after a 3.5 hour delay, with all passengers on board. “Exceeded FA time” That’s why Delta is leading this industry in the US.

Another option for patients with NSCLC and sensitizing EGFR mutations FDA Oncology Keep an eye on DVTs/PEs (36%) and don’t forget the recs for prophylactic anticoagulantion!

FDA approves lazertinib in combination with amivantamab-vmjw for locally advanced or metastatic non-small lung cancer with specific EGFR mutations. fda.gov/drugs/resource… #OCENewsBurst #lcsm

Ever wondered what everyday life was like for people living 50, 100, or more years ago..? A rare thread 1. That’s A Genuinely Happy Looking Family, USA, 1959