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Beautiful review by one of my favorite collaborators The Metanis Group nature.com/articles/s4157…

Primitive purine biosynthesis connects ancient geochemistry to modern metabolism🪨➡️🦠 A collaboration with network expansionistas and world-class peer mentors Josh Goldford and Harrison Smith. Check it out now in NatureEcoEvo nature.com/articles/s4155…

Exciting opportunity at ELSI, Tokyo! We're looking for a Postdoctoral Researcher in Enzymology to join Liam M. Longo Lab. Dive into the world of machine learning and enzymes, exploring ancient reactions. 🧬💻 Apply now or DM with questions! Pls RT! drive.google.com/file/d/1dhd7aq…

【拡散希望】Longo Lab @ ELSI では酵素学者のポスドクを募集しています。 Josh Goldford が共同指導で、機械学習、酵素、古代の生化学を探求するプロジェクトです。 drive.google.com/file/d/1dhd7aq…

Has anyone in human history ever wanted source formatting?

Congrats to Shota, Tommy and all co-authors! Connecting metabolism with TX/TL will be an important stepping stone towards building sustainable synthetic cell🦠

私の興味のある研究を簡単に紹介させてください 。 「生物物理」誌の総説 biophys.jp/journal/journa…

How should we interpret profound sequence conservation, particularly of short motifs? Evidence of simple beginnings? Molecular fossils that have been eroded over time? Caroline Lynn Kamerlin 🇺🇸🇬🇧🇸🇪🇮🇷 ☀️ 🇪🇺🦓 and I teamed up to find out, with Andrey Demkiv leading the charge! biorxiv.org/content/10.110…

Need phosphorylating power? Maybe our universal polyphosphate kinase can help! ATP✅ GTP ✅ CTP ✅ UTP ✅ in vitro transcription ✅ An energizing collaboration with matsuura_tomoaki. Check it out here: biorxiv.org/content/10.110…

Functional Ambidexterity of an Ancient Nucleic Acid-Binding Domain Now out now in Angewandte Chemie Exciting collaboration with The Metanis Group and Levy_research_group onlinelibrary.wiley.com/doi/10.1002/an…

Redefining the Limits of Functional Continuity in the Early Evolution of P-Loop NTPases Now out in Molecular Biology and Evolution Exciting collaboration with Caroline Lynn Kamerlin 🇺🇸🇬🇧🇸🇪🇮🇷 ☀️ 🇪🇺🦓 academic.oup.com/mbe/advance-ar…

Excited to announce that Martina Preiner, Cole Mathis and I were awarded an HFSP research grant! 🎉 If you are an experimentalist interested in studying protein histories as a graduate student in the Longo Lab Earth-Life Science Institute (ELSI) 地球生命研究所, please get in touch.

Happy to share our recent results led by Fukunaga san, a former lab member, now has his own group since Jan 2025 at Miyazaki. Novel and orthogonal riboswitches that can be used in the cell-free system were developed. educ.titech.ac.jp/bio/news/2025_…

Excited to announce that Caroline Lynn Kamerlin 🇺🇸🇬🇧🇸🇪🇮🇷 ☀️ 🇪🇺🦓, Marie Skepö and I were awarded a NASA Exobiology research grant! 🎉 If you are an experimentalist interested in studying protein histories as a graduate student (Earth-Life Science Institute (ELSI) 地球生命研究所) or PostDoc (Blue Marble Space Institute of Science) in the Longo Lab, get in touch!