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Appearing today in Science Magazine : science.org/doi/10.1126/sc…

I thought this paper from Ryan Potts group at Amgen was fascinating. biorxiv.org/content/10.110… It has everything: Chemical induced proximity focused DELs on beads, small decorations on solvent exposed portions of known binder, one bead per well, photocleavable linkers to

Happy to share a new preprint from our group in collaboration with AbbVie led by graduate student ⁦Ines Forrest, Ph.D.⁩ . biorxiv.org/content/10.110…

Over the years we engineered many cell lines expressing various Cas9/dCas9 fusions constitutively or inducibly. I am not ATCC, but if they can be useful to your research, you can get in touch (email, no DM). For some lines you may need an MTA from third parties.

🚀 Excited to share our latest article in #singlecell proteomics published in Cell! SC-pSILAC allows to simultaneously measure protein turnover and abundance in single cells, unlocking the first large-scale, 2D proteomic insights at single-cell resolution! cell.com/cell/fulltext/…

Happy to share our recent contributation to radical chemsitry #Oxa-π, σ-Methane Rearrangement #Epoxide Synthesis J. Am. Chem. Soc. ACS Publications ShanghaiTech University ACS for Authors pubs.acs.org/doi/10.1021/ja…

Save the date! For the first time since 2015, the annual conference of the International Chemical Biology Society comes back to Europe and joins forces with the European Chemical Biology Symposium, to organize #ChemBioParis2025, in the heart of the City of Light. Oct 6-9, 2025

STAR/STARD1: a mitochondrial intermembrane space cholesterol shuttle degraded through mitophagy biorxiv.org/content/10.110…

David Liu wins the Breakthrough Prize in Life Sciences for developing gene-editing technologies, including a "molecular word processor" that can find and replace whole sequences of DNA. His tools are already impacting diseases including cancer. breakthroughprize.org/News/91

Sign up for the European Symposium on Organic Chemistry in Copenhagen. 'Early bird' registation ends on April 11th. esoc2025.com. Prominent speakers include our local 'click-chemistry' expert Professor Morten Meldal (researchprofiles.ku.dk/en/persons/m...).

Large-scale synthesis of delta-cyclodextrin is possible using Enzyme-Mediated Dynamic Combinatorial Chemistry with superchaotropic templates. You can read about it in our latest article in JACS. pubs.acs.org/doi/full/10.10…

GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau nature.com/articles/s4146…

Save the date! For the first time since 2015, the annual conference of the International Chemical Biology Society comes back to Europe and joins forces with the European Chemical Biology Symposium, to organize #ChemBioParis2025, in the heart of the City of Light. Oct 6-9, 2025

📢 Our new preprint is out on bioRxiv! De novo chemo-optogenetics through rational small-molecule design and TRAP display biorxiv.org/content/10.110…

One week until the applications close for our two postdoc positions: 1) Synthetic med chem usyd.wd105.myworkdayjobs.com/USYD_EXTERNAL_… 2) Chem bio usyd.wd105.myworkdayjobs.com/USYD_EXTERNAL_… (new links, not sure why Workday changed them...)

STING mediates lysosomal quality control and recovery through its proton channel function and TFEB activation in lysosomal storage disorders dlvr.it/TKDyHz

🏠Housanes: Our work on the stereoselective synthesis of (oxa)housanes and their skeletal remodeling to access bicyclic imides is out in Chemical Science. Thank you, Anusandhan National Research Foundation IISc Bangalore, for the funding. pubs.rsc.org/en/content/art…

Tubular ER structures shaped by ER-phagy receptors engage in stress-induced Golgi bypass: Developmental Cell cell.com/developmental-…

Terrific study by ⁦Agostinis Lab⁩ and ⁦The ScorranoLab⁩ on the contribution of ER-mito CS to ferroptosis induction nature.com/articles/s4155…