Restriction of individual branched-chain amino acids has distinct effects on the development and progression of Alzheimers disease in 3xTg mice 👉"Our findings suggest that restricting any of the BCAAs, particularly isoleucine or valine, may form the basis of a novel

Tissue-Specific Effects of Dietary Protein on Cellular Senescence Are Mediated by Branched-Chain Amino Acids onlinelibrary.wiley.com/doi/full/10.11…

With boost to NIH budget, Senate panel rejects Trump’s plan to slash agency | Science | AAAS science.org/content/articl…

Another year another mechanism of action for metformin. I think now we have liver AMPK, liver mTOR, microbiome, adipose lipids acting on liver, and now brain… did I miss any?

Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer’s disease 👉 “Our results demonstrate that fasting is a critical component of the benefits of CR on AD, suggesting that fasting alone or fasting-mimicking diets might help to

We are looking to fill the shoes of our lab manager/technician who is starting medical school Monday! If you know someone who might be interested and is passionate about the biology of aging, let them know they can apply here: wisconsin.wd1.myworkdayjobs.com/UW_Madison/job…