Mitochondria from the Outside in: The Relationship Between Inter-Organelle Crosstalk and Mitochondrial Internal Organization - Jonathan R. Friedman, 2022 journals.sagepub.com/doi/10.1177/25…

Nanobodies as novel tools to monitor the mitochondrial fission factor Drp1 biorxiv.org/cgi/content/sh… #biorxiv_cellbio

New! Online now: Nutrient inputs and social metabolic control of T cell fate dlvr.it/T0Ll82

A guide to cell death pathways nature.com/articles/s4158…

WE ARE HIRING! Looking for enthusiastic PostDocs, and post-master degree, to join our group in Tor Vergata, Rome. Studying mitochondrial dynamics new regulators, and T cells’ cross-talk in the tumor microenvironment. Write me soon, Short deadline!! ([email protected])

Lipid accumulation-mediated histone hypoacetylation drives persistent NK cell dysfunction in anti-tumor immunity dlvr.it/T0NdNr

The first tumour-infiltrating lymphocyte (TIL) therapy for cancer could be approved by the FDA early next year, and a diverse pipeline of other TIL candidates is in development - find out more in our latest news article bit.ly/3NldJQE

A great opportunity!! Apply!!! 💪💪💪👇👇👇

Quantitative volumetric analyses and morphological interactions supported by multi-omic profiling identify global organelle defects and mitochondrial dysfunction that can be rescued with ether lipids. nature.com/articles/s4155… #FIBSEM #3D #mitochondria #organelles #lipids

Online now! Metabolic heterogeneity in cancer dlvr.it/T1plRG

"Motion of VAPB molecules reveals ER–mitochondria contact site subdomains" nature.com/articles/s4158…

Now online! Cell surface RNAs control neutrophil recruitment dlvr.it/T1sDxL

cell.com/molecular-ther… Blocking of adipogenic differentiation by #mitochondrial antioxidant may represent a novel strategy to enhance immunosuppressive activity of MSCs in inflammatory microenvironment.

Congratulations to Sarah Cohen (UNC-Chapel Hill) for their new paper on dimerization-dependent fluorescent protein probes (ddFPs) to report membrane contact. This method can be adapted to simultaneously monitor 2 contacts if they share a single organelle.

.Sho Suzuki (he/him) et al Cornell MBG reveal a critical role for Vps13-mediated #lipid transfer at ER–endosome contact sites in ESCRT-mediated sorting, elucidating the contribution of the ER to membrane protein sorting at #endosomes hubs.la/Q02k0rPq0 #Trafficking #ER_literature

Online Now: The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs dlvr.it/T2PF9B

Apoptotic mitochondrial outer membrane permeabilization MOMP is proinflammatory because of mitochondrial membrane protein ubiquitylation leading to NEMO recruitment and NF-kB activation Stephen Tait and colleagues @MitosRUs CRUK Scotland Inst embopress.org/doi/full/10.10…

A string of awards ended the #2024TGdisease: Best overall short presentation (60th FEBS anniversary prize), Best presentation for Clarity and Budding Star...but ALL ECRs WERE AMAZING 🤩FEBS

Elisabetta and Filippo presenting their poster at ISCaM -International Society for Cancer Metabolism 2024 meeting! 💪👏 #cancer #cancermetabolism #mitochondria