Excited to share the preprint of a story Kim Seed, Kristen LeGault, Angus and I put together: Aanti-phage island in Vibrio cholerae evolutionarily constrains a phage-encoded CRISPR-Cas system, leading to different spacers acquired in lab vs clinical 💩 #phage #cholera #CRISPR

Imagine all we could learn if we could crack the genetics of every intractable microbe! We’re on our way #magnetosomes #perserverance

Z. Barth: Vibrio immunity. PLE replication after phage infection produces no phage at lysis. PLE orf is similar to repA and blocks phage replication as it switches replication mode, potentially by hijacking the phage machinery. Way cool. #phages2018 Kim Seed

Happy #WorldElephantDay! Do you know the differences between African and Asian elephants? Learn more: wwf.to/2Med59b

I studied traumatized women for 5 years under an NIH grant and I’m telling you she is 100% credible.

72 hours in Poland sounded like an insane idea, but got to meet all of the Jaenisch family at the biannual fam jam and get a whirwind tour of Silesia and the beautiful town of Wroclaw. It may be because I’m #SleepDeprived but I feel like I’ve been in a fairytale the whole time

Mark your calendars for the momentous 20th anniversary of the Micro Student Symposium, April 27th 2019 in Berkeley CA with keynotes Joe Pogliano and Beth Shanks. Share your memories of the symposium for our special retrospective

New paper showing an example of how the outcome of CRISPR-Cas targeting of a mobile genetic element isn’t always binary. Plus new CR+ phage isolates!

Some days in lab, a literal (phage capsid) light bulb goes on... it’s gonna be a good day

What if all phage disappeared from the world? What if bacteria had no way of defending themselves from page? Today’s “Science Through Story” workshop really got my creative juices flowing. Never thought I’d say this: I can’t wait to give my next talk! Sara ElShafie

A Berkeley resident has tested positive for #COVID19. This individual had been in country with an outbreak and has largely remained at home in a self-imposed quarantine since their return. The risk of infection to the general public remains low. cityofberkeley.info/City_Manager/P…

Preprint of my PhD work from the Seed Lab at UC Berkeley. We show that SXT antibiotic resistance elements encode phage defense systems, and fluctuating SXT dominance determines phage susceptibility in cholera patients. Happy holiday reading! biorxiv.org/content/10.110…

Just finished making some glycerol stocks and realized my strain list is at exactly 666. In honor of the occasion, I’m bumping some Iron Maiden in lab for the first (and probably last?) time.

Mobile antibiotic resistance islands determine epidemic Vibrio cholerae susceptibility to phages! Check out our paper published in Science Magazine science.sciencemag.org/content/373/65…

Ooo and this is a little bit belated, but our preprint describing how a phage parasite antagonizes its viral host is up on bioRxiv Microbiology (I'm such a newbie with this tweeting business 😅). biorxiv.org/content/10.110…

This showed up in the mail. So I guess I’m a doctor now? (Definitely not a photographer, this was the least blurry of like 20 pics 😆)

Tired day spent stumbling around Santiago but the views weren’t wasted on us

Post run rainbow in Chile

Cholera: a public health threat that still causes devastating outbreaks. Nearly a million people are currently suffering from cholera in Yemen, a worrying reminder that #cholera remains a serious and fatal #publichealth problem. newsletter.pasteur.fr/en/newsletters…

Kim Seed Lab throwing up some stiff competition at Lab Moustache Day #moustache @marhtn Kristen LeGault