How do butterflies hide? The Wei Zhang lab integrated data analyses and functional validation to infer the evolutionary history of Kallima and investigate the genetic basis of leaf wing polymorphism. Cell Tsinghua University Peking University #JRNLclub jrnlclub.org/research-films…

Eugene Kwan discusses how multi-substrate optimization of asymmetric reactions leads to broad substrate scope. nature Jacobsen Lab Harvard Chemistry Corin Wagen Harvard University Merck #JRNLclub jrnlclub.org/research-films…

We're proud to share our work in @JeffBiernaskie's Lab U CalgaryVetMed @UCalgary asking why reindeer antler velvet regenerates after wounding whereas back skin forms scar Cell! doi.org/10.1016/j.cell… JRNLclub: jrnlclub.org/research-films… 🦌Atlas: biernaskielab.ca/reindeer_atlas

Great seminar on work out in Cell today! Sarthak Sinha, MD, PhD leveraged regenerative properties of mice and reindeer antler velvet to identify factors that can promote skin regeneration in humans. Jeff Biernaskie @ucalgaryvetmed U Calgary #JRNLclub jrnlclub.org/research-films…

.Jacob H discusses how genetic variation and transcriptional plasticity contribute to intra-tumoral heterogeneity in colorectal cancer. nature Trevor Graham Andrea Sottoriva Centre for Evolution and Cancer, ICR The ICR Human Technopole #colorectalcancer #JRNLclub jrnlclub.org/research-films…

.Nicole S. from the Bryan Yipp lab discusses a new host defense axis relying of innate B cells and neutrophils and how its disruption underlies acquired aspergillosis. Science Translational Medicine UCalgaryMedicine Snyder Institute for Chronic Diseases #JRNLclub jrnlclub.org/research-films…

Happy new year folks! Thanks for tuning in to great science stories. Over 80 talks published this year, and over 370 talks now available JRNLclub. A look back at 2022:

Heather Calcaterra of Mirkin Group discusses utilizing DNA as a flexible "bond" to enable shape memory properties in colloidal crystals. nature International Institute for Nanotechnology Northwestern Engineering NorthwesternResearch tgsatnu #JRNLclub jrnlclub.org/research-films…

Matthew Reynolds discusses the interplay between F-actin biochemistry and mechanics, specifically the effect of F-actin nucleotide state on bending mechanics. nature Matthew Reynolds Alushin_Lab Rockefeller University #JRNLclub jrnlclub.org/research-films…

Jiqin Zhang discusses the development and clinical application of non-viral genome-specific integrated CAR-T technology. nature East China Normal University Zhejiang University #JRNLclub jrnlclub.org/research-films…

Always double check your work. Huanan Herman Zhao discusses extensive off-target editing in the nuclear genome induced by a mitochondrial base editor. nature Chengqi Yi Peking University #JRNLclub jrnlclub.org/research-films…

Always double check your work. Huanan Herman Zhao discusses extensive off-target editing in the nuclear genome induced by a mitochondrial base editor. nature Chengqi Yi #JRNLclub jrnlclub.org/research-films…

New blog up in collab with Amherst STEM Network--A Real Head Turner: Genes Affect Both Brain and Face Shape featuring Sahin Naqvi's paper in NatureGenet, Shared heritability of human face and brain shape. jrnlclub.org/jrnlclub-blog/…

Sung-Wook Hong of the Jenkins lab CFI-UMN explores how the immune system tolerates food antigens we ingest and define a subset of hypo-responsive #CD4 T cells nature UMN DOM Research #JRNLclub jrnlclub.org/research-films…

Hadir Marei Genentech discusses PROTAB technology; an antibody-based degrader platform aimed at targeting cell surface proteins, with Nicholas J Agard and Felipe de Sousa E Melo. nature #JRNLclub jrnlclub.org/research-films…

.Johannes Melms discusses the treatment-naive ecosystem of human melanoma brain metastasis and presents how these differ from extra-cranial metastases. Cell Jana Biermann, Ph.D. @BizarMD @ColumbiaCancer Columbia Medicine #JRNLclub jrnlclub.org/research-films…

.Abbey discusses how rebalancing TGFβ1 and BMP signals in exhausted T cells restores response to immune checkpoint blockade. Nature Immunology Hazem Ghoneim The Ohio State University Wexner Medical Center The James #JRNLclub jrnlclub.org/research-films…

.Yonghoon Kwon discusses the use of fluorescent protein based biosensors in living cells to uncover the importance of spatially compartmentalized receptor signaling. nature Jin Zhang Lab Sohum Mehta Roger Sunahara UC San Diego Research and Innovation Department of Pharmacology, UCSD #JRNLclub jrnlclub.org/research-films…

Leah Billingham of the Nav Chandel lab discusses how the mitochondrial electron transport chain is required for activation of the NLRP3 inflammasome. Northwestern Feinberg School of Medicine Northwestern Nature Immunology #JRNLclub jrnlclub.org/research-films…

.Yuanwei Li discusses a universal method for preparing open channel superlattices with control over crystal symmetry, channel geometry, topology, and resulting properties. nature Mirkin Group Chad A. Mirkin International Institute for Nanotechnology NorthwesternResearch #JRNLclub jrnlclub.org/research-films…