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A family of DNA glycosylases in bacteria that repairs interstrand DNA crosslinks, protects against acid, and is involved in infection. New work from Dillon Kunkle and YUJUAN CAI in collaboration with Brandt Eichman PNASNews pnas.org/doi/10.1073/pn…

Excited to see this detailed view of MntR-oligomerization that is key for Mn-activated transcription in B. subtilis! Work led by Shivani Ahuja and Arthur Glasfeld. Structural basis for transcription activation through cooperative recruitment of MntR biorxiv.org/content/10.110…

N-acetyl-transferases required for iron uptake and aminoglycoside resistance promote virulence lipid production in M. marinum biorxiv.org/cgi/content/sh… #biorxiv_micrbio

A huge step in understanding the biological role of flotillin and membrane microdomains. Led by our very own Marta Ukleja 🇵🇱🙌🙌🙌 with the help of CavaLab, Mateus lab and (twitterless) Ana Eulalio :-). CaixaResearch funding. rdcu.be/dMWvC

The long-awaited structure of Bacillus MntR bound to DNA! While structures of iron-sensing DtxR family members bound to DNA have been known for decades, the DNA complexes of manganese sensors have long eluded structure elucidation. Cryo-EM to the rescue!

Finally published! Check out the final version of our paper describing the discovery of methylolanthanin, a lanthanide metallophore secreted by methylotrophs! pnas.org/doi/epub/10.10…

I’ve felt more than lucky to be able to tour around the US! Thanks to John D. Helmann and his whole lab for being so welcoming and talking some great science (and not science!) with me this week 🧬👩‍🔬

Very excited that this collaborative project is now published. This work was championed by Dr. Yu Tang Yu (Tongji University School of Medicine) and started during a visit to my lab. academic.oup.com/nar/article/do… 1/N

onlinelibrary.wiley.com/doi/10.1111/mm… BLAST Meetings Mol Micro Editors

Membrane depolarization kills dormant Bacillus subtilis cells by generating a lethal dose of ROS Nature Communications from Leendert Hamoen@HamoenLab with Henrik Strahl @KursadTurgay nature.com/articles/s4146…

New in JB: Kochanowsky, Vedantam et al. show that Clostridioides difficile deploys a superoxide reductase to resist the effects of oxygen. journals.asm.org/doi/10.1128/jb… ASM JBacteriology Eds

Our new paper out in PLOS Pathogens today: dx.plos.org/10.1371/journa… We find that resistance/tolerance to antimicrobial peptides is slightly more complex and dynamic than your "average" antibiotic resistance. Nice work by Andrew Murtha et al.!

Read the new story of Robert Warneke (inactive) on coenzyme A biosynthesis in Bacillus subtilis and the identification of a novel metabolite, cysteinopantetheine! Excellent collaboration with Christoph Elfmann @IFeussner and teams! mBio Uni Göttingen #subtiwiki journals.asm.org/doi/10.1128/mb…

🧵 Exciting new findings on bacterial stress response regulation, driven by small proteins (≤50 amino acids). Big shoutout to the amazing team behind this work led by Sangeevan Vellappan (Sangeev). Read the full study here: biorxiv.org/content/10.110…

The evolution and functional significance of the programmed ribosomal frameshift in prfB biorxiv.org/cgi/content/sh… #biorxiv_micrbio

A new study in PNAS explores the connection between methionines and copper, with a focus on CueO. A collaboration between @lcb_officiel and @BIP8_Marseille 🍾🍾 Methionine-rich domains emerge as facilitators of copper recruitment in detoxification systems pubmed.ncbi.nlm.nih.gov/39378088/

I am pleased to announce that our paper describing the role of NusG-dependent RNA polymerase pausing on the function of 5 riboswitches is now published in NAR. academic.oup.com/nar/advance-ar…

🥳A tuneable minimal cell membrane reveals that two lipid species suffice for life: nature.com/articles/s4146…. We chemically minimized the membrane of the Minimal Cell...they survived, but with some interesting shapes, like this 'Death Star' phenotype Isaac J. Craig Venter Institute

Curious about organelle biogenesis in bacteria 🦠🔬Check out our review on bacterial organelles and their role in iron physiology Mol Micro Editors doi.org/10.1111/mmi.15…