Jesse Engreitz
@jengreitz
Assistant Professor @stanford Genetics and BASE Initiative. Mapping the regulatory code of the human genome to understand heart development and disease.
ID: 184238046
http://www.engreitzlab.org 29-08-2010 01:43:27
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We report a new CRISPR resource, Fragmid, in Cell Genomics today, let by the incomparable Abby McGee. Let's walk through it… cell.com/cell-genomics/…
An Analysis presents a collection of non-coding CRISPRi screens from the ENCODE4 Functional Characterization Centers and establishes experimental guidelines for future screens identifying cis-regulatory elements. Steve Reilly nature.com/articles/s4159…
What a PERFFect day to share our new preprint! With Tsion Abay #BobStickels Meril Takizawa Ronan Chaligne (He/Him) and Ansu Satpathy, we introduce PERFF-seq, a new experimental approach to studying rare cells with scRNA-seq via transcript-specific enrichment. biorxiv.org/content/10.110… 1/n
Our paper "A machine readable specification for genomics assays" is now published in Bioinformatics, OUP Bioinformatics. In short, we present a lightweight file format and command-line tool to document the structure of sequencing reads. Coauthored with Xi Chen and Lior Pachter. Paper:
Check out ProCapNet by Kelly Cochran, a robust, local sequence context deep learning model of base-resolution transcription initiation profiles (PRO-cap) that provides deep insights into the cis-regulatory code of initiation & more ... biorxiv.org/content/10.110… 1/
Sometimes simple models, proposed years ago, turn out not so bad! This preprint shows that E-P interactions control expression, that cohesin helps mediating these interactions, esp. for distal enhancers (>50kb), see also work from Wendy Bickmore in NSMB. doi.org/10.1101/2024.0…
Exciting news! Jesse (Jesse Engreitz), Marlene (Stanford BASE), and I have recently received a CIRM grant, and we presumably ranked No. 1 based on the prior year's criteria! I am looking for a talented experimental postdoc to join my team. This position offers close collaboration
(1/16) Check out our Simon Gaudin paper tiny.cc/icuazz from the Canzio lab out in Science Magazine today on how tuning local cohesin trajectories enables differential readout of the clustered Protocadherin (Pcdh) locus across different types of neurons.
Excited to share the white paper for the IGVF Consortium, supported by National Human Genome Research Institute Deciphering the impact of genomic variation on function rdcu.be/dSZdm