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#ToRememberOrNotToRemember? Sarah Sun Luis B Barreiro &co show Immunity that after human BCG vaccination, transcription is changed in stem cells while chromatin changes lasting 90 days happen in progenitor cells & correlate with IL1b release by PBMCs! doi.org/10.1016/j.immu…

Online now: An explainable language model for antibody specificity prediction using curated influenza hemagglutinin antibodies dlvr.it/TC85LG

Online now: Affinity-independent memory B cell origin of the early antibody-secreting cell response in naive individuals upon SARS-CoV-2 vaccination dlvr.it/TC8VD4

Memory B cells with similar Ag reactivity as naive B cells rapidly differentiate into ASCs without GC re-entry, whereas affinity maturation of naive B cells underlies improved humoral immunity vs novel antigens Immunity Hedda Wardemann Anna Obraztsova cell.com/immunity/fullt…

OBS Seminar Immune Cell migration and regulation across tissues 📆 Thu, 08/29/2024 8 am PT/11am ET/3pm GMT/5pmCEST 🎙️ Dr. Silvia Galván Peña Harvard Medical School @umasschan Science Immunology 🎙️ Orian Bricard Adrian Liston Cambridge Pathology Immunity Registration 👇 us02web.zoom.us/meeting/regist…

Online now: PD-1 signaling limits expression of phospholipid phosphatase 1 and promotes intratumoral CD8+ T cell ferroptosis dlvr.it/TCTsBb

Online now: CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes dlvr.it/TCX7fv

Online now: CD4+ T cells re-wire granuloma cellularity and regulatory networks to promote immunomodulation following Mtb reinfection dlvr.it/TCXTLD

Exhilarated to share the first original study from my lab published online Immunity. A great team endeavor spearheaded by the fantastic Sofia Pereira Das Neves 😁 “Meningeal lymphatic function promotes oligodendrocyte survival and brain myelination” authors.elsevier.com/a/1jhWg3qNrUxu…

1/9 I am very excited to share our most recent publication in Immunity , the work we developed for the last 3 years at the Sandro Da Mesquita lab: “Meningeal lymphatic function promotes oligodendrocyte survival and brain myelination”. See 🧵 below sciencedirect.com/science/articl…

Online now: Meningeal lymphatic function promotes oligodendrocyte survival and brain myelination dlvr.it/TCc8js

Check out this nice thread wrote by 1st author Sofia Pereira Das Neves summarizing the main findings of our paper “Meningeal lymphatic function promotes oligodendrocyte survival and brain myelination”, out today online Immunity 😃

Autoantigen-specific CD4+ T cells acquire an exhausted phenotype and persist in human antigen-specific autoimmune diseases Check out this work by Carina Saggau, Petra Bacher, Alex Scheffold et al Immunity, to which we had the pleasure to contribute. sciencedirect.com/science/articl…

Online now: Autoantigen-specific CD4+ T cells acquire an exhausted phenotype and persist in human antigen-specific autoimmune diseases dlvr.it/TCjl4b

Conventional anticoagulant therapies to prevent thrombosis also carry inherent bleeding risks, but therapeutic complement inhibition prevents thrombosis without negatively impacting hemostasis Immunity cell.com/immunity/fullt…

Check out this elegant work led by Sofia Pereira Das Neves & Sandro Da Mesquita on #lymphatics, #oligodendrocytes & #myelination just published Immunity. Many congrats to them and all co-authors. Happy to have contributed with #lipidomic analysis.

Online now: Antibodies and complement are key drivers of thrombosis dlvr.it/TCk6g5

#CoagulationPower! Stark &co show Immunity that antigen-independent activities of antibodies drive pathological coagulation! IgM activate endothelial cells that recruit platelets that bind IgG inducing #complement activation, NETosis & thrombosis dlvr.it/TCk6g5

what a #beautiful #paper Immunity Autoantigen-specific CD4 T cells acquire an exhausted phenotype and p... sciencedirect.com/science/articl…

Online now: Inhibitory co-receptor Lag3 supports Foxp3+ regulatory T cell function by restraining Myc-dependent metabolic programming dlvr.it/TCq1YD