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P37: "Design, synthesis, biological evaluation and binding studies of new sub-nanomolar inhibitors of CARM1 (PRMT4)." DCF-SCI #DCFSCI #NPCF13 #EPIGENETICS

Hello everyone! I’m Giulia Iannelli, a PhD student at EpigeneticMedChemLab Università Salerno My poster (PC_28) is focused on design, synthesis, biological evaluation and binding studies of new sub-nanomolar inhibitors of CARM1 (PRMT4). Net4Science #PEVM2021 #medchem

Our work on deconstruction–reconstruction approach turning non-selective type I PRMT inhibitors into potent and selective PRMT4 inhibitors is now available (open access) in ACS Publications Bio & Med Chem Content JMC (asap). Thanks to all coauthors! EpigeneticMedChemLab   shorturl.at/bnuEZ

Kicking off the sulfur meeting in vienna. If you follow the red arrow you’ll see where Einstein used to sit. #JWOCS23

First speaker of #JWOCS23 is Ritter Lab with late-stage functionalisations on show! Max Planck Society Kyoto University University of Vienna STEM

A nice collaboration with Steve Clarke (⁦⁦UCLA Chem & Biochem⁩), Yanzhong Yang (⁦City of Hope⁩) and ⁦Sandro Cosconati⁩ work on the identification of a PRMT7PRMT9 inhibitor, just published in J. Med. Chem. ⁦ACS Publications Bio & Med Chem Content⁩. pubs.acs.org/doi/10.1021/ac…

Congratulations to all the members of the EpigeneticMedChemLab team. AlessandraFeoli Giulia Iannelli Alessandra Cipriano Monica Viviano Ciro Milite Giuliana Sarno Sabrina Castellano and to Maria Chiara Monti and Elva Morretta (Università Salerno Dept. of Pharmacy)

The latest issue of #JMedChem is out! go.acs.org/6tG ▶️Read the cover story by Gianluca Sbardella and coworkers where they report the identification of the first potent PRMT7/9 inhibitor.

Merry Christmas! 🎄Amidst the pursuit of high-impact papers/grants, let’s remember what truly illuminates academia: the minds we are allowed to shape. From undergrads to Postdocs, each person is a spark we ignite. Here’s to the next generation of thinkers. 🌟 Universität Wien #nunopost

It’s out! Check our nature publication about charge relocation! nature.com/articles/s4158… Congratulations to the team! #Bogdan Giulia Iannelli @el_salato #oxacarbeniumgang

Amazing work! Congratulations to Nuno and all the authors of the MaulideGroup involved (especially Giulia Iannelli, of course, but I’m biased 😊)! EpigeneticMedChemLab

Ein Team unter Leitung von MaulideGroup hat eine neue Methode zur Umwandlung von #Alkenen in komplexere Produkte entwickelt. Alkene sind Bausteine, die in versch. Bereichen nötig sind & deren Transformation in andere Produkte von besonderem Interesse ist. medienportal.univie.ac.at/media/aktuelle…

Huge gratitude to WhiteGroup , for delivering a brilliant and outstanding talk on Late-Stage Functionalization! #alpinewinterconference

Proudly announcing that our group member Giulia Iannelli, one of the first authors of our first nature publication, brilliantly presented their work in a poster at the 4th Alpine Winter Conference of the EFMC. Congratulations! #OrganicChemistry #Nature #TwitterGang

Best thing about the conference was meeting brilliant young scientists like Giulia Iannelli ! If you have not yet read her nature paper from the MaulideGroup group make sure you check it out: doi.org/10.1038/s41586…