Demis Hassabis explains how the new AlphaFold 3 will build on DeepMind's previous work to accelerate drug discovery and design

I think if you care about the debates over ethics & AI, it is worth reading the OpenAI Model Spec. It is the first comprehensive attempt to actually lay out the practical principles under which AI operates, by a lab actually building them. Lots there. cdn.openai.com/spec/model-spe…

Given the small number of people who use frontier models today, I think many people who found AI useless when using the free version of ChatGPT are going to be shocked by the capabilities when GPT-4o is made freely available worldwide. Expect a burst of concern & excitement.

Civilization VII was announced today. The Civ series is sort of like Ender’s Game, but for management rather than murdering aliens. Business school students who were good at Civ V also turn out to be better planners, organizers, and problem-solvers, in this small experiment.

The distribution of house sizes in France looks a lot like the distribution of business sizes, and for the same reason: a regulation that kicks in at a certain size.

Awesome result on a way in which AIs can outperform all the individual human experts whose data it is trained on: the AI is effectively aggregating the wisdom of the expert crowd. When trained on diverse expert knowledge, the AI acts like a majority vote, which beats individuals

FOUR key things in the past 20-30 years are causing the physical world to electrify: 1) magnets got way better, enabling high torque permanent magnet motors.

This website is offering to let me negotiate with an AI to buy a mattress

“AGI Alignment?” replied the VP of Research incredulously. “Wait, and you said you’ve been…” He furrowed his brow. “…‘offline’ for the past quarter, doing ‘deep work’?” “Yes. Don’t tell me the whole team was disbanded and nobody texted me?” He laughed. “Oh, you mean like the

An incredible experience beyond imagining to get to sign the great Nobel book, alongside many of my all-time scientific heroes: Einstein, Curie, Bohr, Planck, Schrodinger, Crick, Feynman…

New randomized, controlled trial of students using GPT-4 as a tutor in Nigeria. 6 weeks of after-school AI tutoring = 2 years of typical learning gains, outperforming 80% of other educational interventions. And it helped all students, especially girls who were initially behind

Tesla sold more Model Ys in the US in Q4 2024 than the total combined sales of all EV models sold by Toyota, VW, Rivian, Porsche, Mercedes, Kia, Honda, Ford, Volvo, Fiat and Lexus during the same period.

They actually did it.  Boom is officially the first independently developed supersonic jet.

"Move 37" is the word-of-day - it's when an AI, trained via the trial-and-error process of reinforcement learning, discovers actions that are new, surprising, and secretly brilliant even to expert humans. It is a magical, just slightly unnerving, emergent phenomenon only

Semi-controversial opinion I think is truer the older I get: There’s no such thing as working too hard. There’s just being under rested. 1. Winston Churchill used to work 16 hours per day in his old age during the war — but he also worked in bed every day until 11am. He had a

This is Feynman's last blackboard - "What I cannot create I do not understand"

This better be the last time the time changes.

Some people today are discouraging others from learning programming on the grounds AI will automate it. This advice will be seen as some of the worst career advice ever given. I disagree with the Turing Award and Nobel prize winner who wrote, “It is far more likely that the

The future is unevenly distributed.

The largest volcano in the solar system (Olympus Mons) overlaid on Arizona