Michael Fralick (@fralickmike) 's Twitter Profile
Michael Fralick

@fralickmike

Clinician Scientist @SinaiHealth | amateur golfer/gardener/barista | fralicklab.com | medicinepods.com | jrnowl.com | trialfiles.substack.com

ID: 2518423562

linkhttps://www.youtube.com/@Fralickmike/videos calendar_today23-05-2014 18:28:02

4,4K Tweet

3,3K Followers

443 Following

Michael Fralick (@fralickmike) 's Twitter Profile Photo

Are you a medical student or resident? Do you like freshly baked cookies? If you answered yes to either, we've created a playlist of podcast episodes from The Intern At Work & The Rounds Table covering all things cardiology. 🍪🎙️🏥🩺 Feedback welcomed: shorturl.at/rRz3C

Medicine Pods (@medicinepods) 's Twitter Profile Photo

📊 What is logistic regression, and why is it everywhere in medical research? In just 5 minutes, Michael Fralick explains how it works, when to use it, and what those odds ratios really mean — no stats degree required. 🎥: youtube.com/watch?v=Qq1J20… #LogisticRegression #MedTwitter

Medicine Pods (@medicinepods) 's Twitter Profile Photo

The latest edition of qMonthly is here! This month's takeaways: ✅ No benefit to fluid restriction in stable HF ✅ Thoracentesis doesn’t improve outcomes in HF-related effusions ✅ SGLT2i after TAVI cuts CV events in select HF pts 📩: medicinepods.com/mailing-list/ #MedTwitter #EBM

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🧪 This week in Trial Files: 🧓 CGM + geriatric care = ↓ hypoglycemia in older T1D adults 💉 LAA closure ≈ OAC for stroke prevention, but ↓ bleeding 🧠 Alteplase 4.5–24h post-stroke = ↑ function in posterior strokes 🔗 trialfiles.substack.com/p/trial-files-… #T1D #Stroke #AFib

🧪 This week in Trial Files:

🧓 CGM + geriatric care = ↓ hypoglycemia in older T1D adults
💉 LAA closure ≈ OAC for stroke prevention, but ↓ bleeding
🧠 Alteplase 4.5–24h post-stroke = ↑ function in posterior strokes

🔗 trialfiles.substack.com/p/trial-files-…

#T1D #Stroke #AFib
Medicine Pods (@medicinepods) 's Twitter Profile Photo

🩸 New Thrombo Trials! 🔹 Reduced-dose DOACs ≈ full-dose for VTE recurrence but didn’t meet non-inferiority; ↓ bleeding risk 🔹 PCC > plasma for bleeding control in cardiac surgery 🔹 Alteplase 4.5–24h: ↑ function in posterior stroke 🔗 thrombotrialfiles.substack.com/p/thrombo-tria… #VTE #DOACs

🩸 New Thrombo Trials!  

🔹 Reduced-dose DOACs ≈ full-dose for VTE recurrence but didn’t meet non-inferiority; ↓ bleeding risk
🔹 PCC > plasma for bleeding control in cardiac surgery
🔹 Alteplase 4.5–24h: ↑ function in posterior stroke

🔗 thrombotrialfiles.substack.com/p/thrombo-tria…

#VTE #DOACs
Medicine Pods (@medicinepods) 's Twitter Profile Photo

This week, @Roundstable has a solo episode with Dr. John Fralick discussing a recently published trial of the GLP-1 receptor agonist semaglutide for the treatment of metabolic dysfunction–associated steatohepatitis (MASH). Listen now at medicinepods.com‼️🎙️💉

Medicine Pods (@medicinepods) 's Twitter Profile Photo

🎙️New Episode Alert! This Sunday, The Intern At Work is back with "Putting Out the Fire: A Clinical Approach to Adult Onset Still’s Disease!" 🔥Tune in at medicinepods.com for clinical insights, and the episode infographic❗️

Medicine Pods (@medicinepods) 's Twitter Profile Photo

🎙️ Your ultimate med podcast roundup! Tune in and level up your medical knowledge! 🌟 Beyond MD: medicinepods.com/beyond-md-with… 🌟 Rheum for the RC: medicinepods.com/rheum-for-the-… 🌟 JAMA Clinical Reviews JAMA: jamanetwork.com/journals/jama/… #MedTwitter #EBM #InternalMedicine

Medicine Pods (@medicinepods) 's Twitter Profile Photo

🫁 Confused by ABGs? Michael Fralick's one-pager makes sense of: ✅ Metabolic and respiratory acidosis/alkalosis ✅ Causes of acid-base disorders ✅ Key compensation patterns 📖 Grab the full book here: amazon.ca/One-Pagers-War… #MedTwitter #InternalMedicine

Michael Fralick (@fralickmike) 's Twitter Profile Photo

💊 Think you’ve got drug interactions covered? You’re probably missing these ones. Tune into today's The Rounds Table podcast where i interview David Juurlink and he helps to demystify drug interactions and shares high-yield pearls. open.spotify.com/episode/3ZucwL… Medicine Pods

Medicine Pods (@medicinepods) 's Twitter Profile Photo

🎙️This week we have a special podcast episode by The Rounds Table. Dr. Michael Fralick sits down with Dr. David Juurlink, a pharmacologist and internist, to discuss the top drug interactions you may be missing. Listen now at medicinepods.com‼️

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🚨 New qMonthly is out! Tirzepatide > semaglutide for weight loss (20% vs 14%) Semaglutide works for MASH (62% vs 34% placebo) Brensocatib cuts bronchiectasis exacerbations by 20% 📩 Sign up to get the full scoop: medicinepods.com/mailing-list #InternalMedicine #EBM #MedTwitter

🚨 New qMonthly is out!

Tirzepatide > semaglutide for weight loss (20% vs 14%)

Semaglutide works for MASH (62% vs 34% placebo)

Brensocatib cuts bronchiectasis exacerbations by 20%

📩 Sign up to get the full scoop: medicinepods.com/mailing-list

#InternalMedicine #EBM #MedTwitter
Medicine Pods (@medicinepods) 's Twitter Profile Photo

📚 Throwback Trials: 💊 SPACE: Opioids = Non-opioids for chronic pain, but ↑ side effects 💉 Albumin in SBP: ↓ renal failure & death when added to cefotaxime 🩺 Omeprazole pre-endoscopy: ↓ need for endoscopic therapy 🔗 trialfiles.substack.com #Opioids #SBP #MedTwitter

📚 Throwback Trials:

💊 SPACE: Opioids = Non-opioids for chronic pain, but ↑ side effects
💉 Albumin in SBP: ↓ renal failure & death when added to cefotaxime
🩺 Omeprazole pre-endoscopy: ↓ need for endoscopic therapy

🔗 trialfiles.substack.com

#Opioids #SBP #MedTwitter
Medicine Pods (@medicinepods) 's Twitter Profile Photo

🎙️Welcome back @Roundstable Listeners! Today, we have a solo episode with Dr. Michael Fralick where he discusses a recently published head-to-head trial exploring the safety and efficacy of tirzepatide compared to semaglutide for obesity management!💉

Mats C. Højbjerg Lassen, MD (@matslassen) 's Twitter Profile Photo

Pooled analysis of obesity and kidney outcomes from 4 HFpEF RCTs now in JACC Journals 👥 n=16,919 ⬆️ waist circumference ➡️ higher kidney risk🫘🏥 ⬆️ waist-to-height ratio ➡️ higher kidney risk 🫘🏥 But not for BMI 🤔 sciencedirect.com/science/articl… Muthu Vaduganathan Tor Biering-Sørensen, MD, MSc, MPH, PhD

Pooled analysis of obesity and kidney outcomes from 4 HFpEF RCTs now in <a href="/JACCJournals/">JACC Journals</a> 

👥 n=16,919

⬆️ waist circumference ➡️ higher kidney risk🫘🏥

⬆️ waist-to-height ratio ➡️ higher kidney risk 🫘🏥

But not for BMI 🤔

sciencedirect.com/science/articl…
<a href="/mvaduganathan/">Muthu Vaduganathan</a> <a href="/TorBiering/">Tor Biering-Sørensen, MD, MSc, MPH, PhD</a>
Medicine Pods (@medicinepods) 's Twitter Profile Photo

🎙️ New on The Rounds Table: Trial Files Debut! Dr. Michael Fralick breaks down 3 key clinical trials in 9 minutes: 💊 Opioids vs non-opioids for chronic pain 🩸 IV albumin in renal impairment 🔍 Omeprazole before endoscopy in GI bleed Listen now 👉 medicinepods.com 📑

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Welcome back, The Rounds Table listeners! Trial Files turns 2! 🎉To celebrate, Dr. Michael Fralick recaps the Top 5 RCTs from our catalogue — all in just 15 minutes. Tune in now on medicinepods.com‼️

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🎉 Trial Files Turns 2! Our Top 5 Picks: 🩸 Restrictive vs liberal transfusion in MI: no clear winner 🧠 Semaglutide ↓ kidney & CV events in T2D 🦵 Semaglutide ↓ weight & knee OA pain 🦠 7 days abx = 14 days for BSI ❤️ Finerenone ↓ HF events in HFpEF trialfiles.substack.com

🎉 Trial Files Turns 2! 

Our Top 5 Picks:
🩸 Restrictive vs liberal transfusion in MI: no clear winner
🧠 Semaglutide ↓ kidney &amp; CV events in T2D
🦵 Semaglutide ↓ weight &amp; knee OA pain
🦠 7 days abx = 14 days for BSI
❤️ Finerenone ↓ HF events in HFpEF

trialfiles.substack.com