Happy to share our preprint on a tool that prototypes #cryoEM metadata harvesting! EMinsight analyses and reports on microscope configuration and experimental outcomes. We see potential applications in making data driven decisions, archiving, ML and more. doi.org/10.1101/2024.0…

The next #CryoEM Current Practices Webinar speaker will be Dr. Castells-Graells from the University of California. Join us 2/29/24 at 12 PM ET / 9AM PT📷 Registration is at no-cost, but sign-up is required: cryoemcenters.org/events/

I am looking for a postdoc to work on understanding mechanisms of gene expression in the chloroplast 🧬🌿. An opportunity for someone interested in doing cryo-EM ❄️🔬and biochemistry 👇

How photosynthetic genes are transcribed 🧬🌿 I’m really pleased to share the first work from my group at John Innes Centre published today in Cell: cell.com/cell/fulltext/…

Excited to share our latest research on leveraging machine learning for the design of novel protein cages! Using cryo-EM, we've successfully solved their structures, achieving 2 Å resolution for one of our designs. #proteincages #ml #CryoEM Link: cell.com/structure/full…

High-res In-situ Structures of Mammalian Respiratory Supercomplexes in Reaction within Native Mitochondria biorxiv.org/content/10.110… Check out my lab's first work on membrane proteins! Yes, we knew nothing about detergent😜, so we directly imaged proteins within native membrane!

New activity on the Chan Zuckerberg Imaging Institute’s CryoET Data Portal bit.ly/3T9sZ6D ; segmentations can now be visualized in the browser for 15,000+ tomograms. We would love feedback bit.ly/3VUcHjc on how we can improve and expand.

Check out NuA4/TIP60 in Science Magazine . We show how this molecular Swiss army knife integrates histone exchange and acetylation in one complex to maintain genome stability 🧬 Congrats to zhenlin and @mameri_amel who co-first authored this work! 🧵⬇️ twtr.to/157Oh

Structural insights into the chloroplast protein import in land plants: Cell cell.com/cell/fulltext/…

Excited to share our latest manuscript on virus maturation! We've successfully solved the structures of five intermediates in the NωV maturation process and unraveled the intricate structural reorganization required for infection. biorxiv.org/content/10.110…

Super excited to share our latest work on the native in-cell organization of the mitochondrial respiratory chain 🥳 Using cryo-electron tomography🔬, we show how the respiratory complexes (and other complexes) are organized inside native mitochondria!  biorxiv.org/content/10.110…

BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

CryoET curious? Check out this upcoming webinar- talks from Elizabeth Wright and David Stuart + demo of the Arctis plasma FIB SEM with app results Registration is now open for the webinar- Nov 13 from 11am-1pm ET (5pm CET)- ter.li/nonxc8 bit.ly/4hqrnzk

I'm a PhD student at University of Oxford and I think I'm living in a fairytale :-) Foxes playing around in the snow at Magdalen College this morning — absolutely magical!

I have a PhD studentship available to join my lab (near Nottingham, UK) in October 2025 for an exciting project in collaboration with a commercial partner (CASE studentship). Interested students must apply through the BBSRC DTP programme: nottingham.ac.uk/bbdtp/apply/ho… Please share!

I’m looking for a postdoc to join my team under a recently funded ERC Starting Grant. If you’re passionate about structural #virology and have experience in #cryoEM SPA and/or #cryoET, get in touch! Deadline: January 19th. Please share 🙏 tiny.cc/7v33001

I feel very excited to share our latest work (now in preprint) on the nuclear import of HIV-1. Employing correlative cryo-ET, we captured nearly 2000 HIV-1 cores associated with the nucleus. Find more in the paper 😆

I’m delighted that we could contribute the #cryoEM data to this incredible antiviral discovery project from the group of Johan Neyts 💊 Published today in Nature: nature.com/articles/s4158… A huge congrats to everyone involved! 🎉

#CryoSPARC v4.7 is out! 🚀  Featuring a new automatic Micrograph Junk Detector that labels and rejects contaminants, new tools for curating subsets of particles, performance and stability fixes, and more! Full changelog: cryosparc.com/updates #cryoEM

Interested in our recent norovirus NS3 work? 👇 Join us to dig deeper! I'm recruiting a PhD candidate to investigate NS3's role in viral replication and assembly using #cryoEM, #cryoET, and other complementary techniques. 🔗 tinyurl.com/4f3t3aae Please share! 🙏