It's absolutely vital to examine just how accurate our cell models are. Thanks to everyone involved for their hard work! 🎊

The University of Liverpool has launched a new spin-out company, TrophiCell, that has developed a revolutionary approach to harness the therapeutic potential of adult MSCs. bit.ly/3wenIRX

Researchers at université de Franche-Comté conducted an analysis of the transplacental transmission of #SARSCoV2 virus and antibody transfer according to the gestational age at maternal infection, and confirmed the very low rate of SARS-CoV-2 transplacental transmission. go.nature.com/4bBa9MC

Researchers at Hebei Medical University find evidence suggesting that monosialoteterahexosyl ganglioside (GM1) is an effective agent to induce the differentiation of human umbilical cord MSCs into neuron-like cells. bit.ly/3SGu6sL

A Johns Hopkins Medicine team shows that the primed pluripotent state can generate trophoblast stem cells by activating pathways such as EGF and WNT, and by suppressing TGFβ, HDACs, and ROCK signaling pathways, all without the addition of exogenous BMP4. go.nature.com/49CFZqr

Researchers fabricated an injectable hydrogel loaded with umbilical cord MSCs via the Diels-Alder click reaction, which exhibited unique bioorthogonality, and could adapt to the intricate anatomy of the #uterus. bit.ly/3OHVvti

A hydrogel prepared from decellularized human umbilical cord tissue was developed and evaluated for osteochondral regeneration. Read the researchers' findings below 👇 : bit.ly/3I3hSWb

🚀 While training for an upcoming space mission was underway, two NASA Flight Engineers, Jasmin Moghbeli and Loral O’Hara, focused the majority of their day on the Mesenchymal Stem Cells in #Microgravity Induced Bone Loss investigation. go.nasa.gov/3SCIP82

Scientists constructed CD38 antigen receptor membrane-modified MSC-extracellular vesicles by transfecting MSCs with a lentivirus loaded with a CD38 antigen receptor–CD8 transmembrane fragment fusion plasmid to target AEC2s and alleviate #PulmonaryFibrosis. bit.ly/3wpHhXJ

Cellenkos has received approval to advance to the second cohort of patients in its clinical trial of neurotrophic T regulatory cell therapy CK0803 for ALS treatment. bit.ly/4bOgN2g

More than three months after Health Canada issued a public health warning about the Canadian Cord Blood bioRepository facility in west Edmonton, a local couple no longer trust that the stem cells they have preserved there remain viable or safe. bit.ly/3OVm7qR

A team at UBC Ob/Gyn including Dr. Alexander Beristain evaluates how primary and stem cell-derived human trophoblast organoids reproduce developmental cell trajectories and transcriptional regulatory processes defined in vivo. bit.ly/42SEnqu

📢Now #online a collaborative work with Dr. Martí Lecina’s lab IQS on the #Identification of #critical #process #parameters for expansion of #clinical grade human Wharton's jelly-derived #mesenchymal stromal cells in stirred-tank #bioreactors 🔗doi.org/10.1002/biot.2…

The regulated cell death at the maternal-fetal interface: beneficial or detrimental? Sun Yat-sen University authors discuss how regulated cell death serves as a mode of communication between different cells throughout placental development and pregnancy. go.nature.com/4bUKmiO

A team of researchers at MIT Dept of BE and Vincent Center for Reproductive Biology including Dr. Edlow investigated placental transfer dynamics and durability of maternal #COVID19 vaccine-induced antibodies in infants, finding they persisted in most infants through 6 months. bit.ly/48AROfQ

FBLN1 is critical for regulating the osteogenic differentiation potentials of umbilical cord mesenchymal stem cells and have identified that miR615-3p mediated the decay of FBLN1 mRNA which facilitated by m6A reading protein YTHDF2. onlinelibrary.wiley.com/doi/10.1111/cp…

Investigators demonstrated that FBLN1 was critical for regulating the osteogenic differentiation potentials of umbilical cord MSCs and identified that miR615-3p mediated the decay of FBLN1 mRNA which was facilitated by m6A reading protein YTHDF2. bit.ly/3uSBTM9

Wharton's jelly-MSCs were readily expanded in stirred-tank #bioreactors with two media, preserving critical quality attributes in terms of identity, viability, and differentiation potency, and yielding up to 1.47 × 10^9 cells in a real-scale 2.4-L batch. bit.ly/3SQUoZo

Researchers report that the administration of human umbilical cord MSCs 12 hours prior to surgery could significantly improve the survival rate of rats with #AcuteLiverFailure, in part by inhibiting the secretion of inflammatory 🔥 factors. bit.ly/3TlF2ha