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Join us today for late-breaking results of the CLEAR OASIS 9 trial! #CardioTwitter

A new article from our Ethics and Regulatory Core highlights the value of informing participants about research conducted under a waiver of consent. #bioethics #pragmatictrials Read more ➡️ duke.is/pctnews20250422

📣 In this Friday's PCT Grand Rounds, Ming Tai-Seale of UC San Diego will discuss integration of automated response technology into EMR and patient-physician communication. Join us! #pctGR 🔗 duke.is/pctnews20250423

📣 In this Friday's PCT Grand Rounds, Roland RJ Kimmenade of Radboud University will discuss the FRESH-UP study of fluid restriction in #heartfailure vs liberal fluid uptake. Join us! #pctGR #CardioTwitter 🔗 duke.is/pctnews20250430

Join us today for a discussion of the FRESH-UP trial! #CardioTwitter #pctGR

📣 In this Friday's PCT Grand Rounds, Andrea Cook of KP WA Research, Lynn DeBar of Kaiser Permanente Center for Health Research, and Patricia Herman of RAND will present the results of BackInAction, an NIH Collaboratory Trial of #acupuncture for #LowBackPain. Join us! 🔗 duke.is/pctnews20250507 #pctGR

The NIH Pragmatic Trials Collaboratory (NIH Pragmatic Trials Collaboratory), led by NIH NCCIH and The National Institute on Aging (NIA), has pioneered approaches for conducting large-scale, cost-effective research in the settings where patients normally receive their care. Learn more from this video: bit.ly/432Kklc

TODAY! Be one of the first to learn the results of BackInAction, an NIH NCCIH-supported, policy-relevant pragmatic trial of standard and advanced courses of #acupuncture vs usual care for older adults with chronic low back pain. duke.is/pctnews20250507

ICYMI Researchers in our Distributed Research Network applied the “target trial emulation framework” to illustrate the potential for observational studies of #RealWorldData to emulate randomized #ClinicalTrials in early Alzheimer disease. duke.is/pctnews20250417

📣 In this week's PCT Grand Rounds, Jeffrey Spaeder of IQVIA will join NIH Collaboratory co-principal investigator Adrian Hernandez Adrian “WE NEED RCTS!” Hernandez of Duke University School of Medicine to discuss the future of clinical trials in a new and changing world. Join us! #pctGR 🔗 duke.is/pctnews20250512

Results from ACP PEACE are in! This pragmatic clinical trial supported by The National Institute on Aging (NIA) assessed whether a combined patient and clinician intervention increased the rate of #AdvanceCarePlanning among older patients with advanced cancer. Read more ➡️ duke.is/pctnews20250513

📚 A new chapter in our Living Textbook of Pragmatic Clinical Trials addresses end-of-trial decision-making, including whether to sustain the intervention in the period between when the trial ends and when the results are known. Read more ➡️ duke.is/pctnews20250514.

ICYMI The results of our ACP PEACE study appear in this month's issue of JAMA Network Open. Learn more about the combined patient and clinician intervention that improved rates of #AdvanceCarePlanning among older patients with advanced cancer.

💡Grand Rounds: DCRI Executive Director Adrian Hernandez and IQVIA Senior Vice President Jeffrey Spaeder will discuss the future of clinical trials this Friday at 1 p.m. NIH Pragmatic Trials Collaboratory Details: duke.is/pctnews20250512 Duke Clinical Research Institute Duke University School of Medicine

🎙️ In the latest episode of our Rethinking Clinical Trials Podcast, hear from Angelo Volandes and James Tulsky about the results of the ACP PEACE trial, published this month in JAMA Network Open. duke.is/pctnews20250519

Our new learning module, Healthcare Data Interoperability and Standardization for Research, describes collecting healthcare data in the #EHR and optimizing these data for improved patient and research outcomes. duke.is/pctnews20250528

📣 In this Friday's PCT Grand Rounds, Ankeet Bhatt Ankeet S. Bhatt, MD, MBA of the Kaiser Permanente Division of Research Kaiser Permanente Research NorCal will discuss the KP-VACCINATE megatrial and embedding randomization into clinical care. Join us! #pctGR 🔗 duke.is/pctnews20250530

📣 In this Friday's PCT Grand Rounds, Jon Casey of Pragmatic Critical Care Research Group at Vanderbilt Health will discuss a REDCap advanced randomization module from the Trial Innovation Network. Join us! #pctGR 🔗 duke.is/pctnews20250604

📣 In this Friday's PCT Grand Rounds, Stephanie Morain, Nancy Kass, and Ruth Faden of the Johns Hopkins University Berman Institute will discuss improving the ethical oversight of pragmatic clinical trials. Join us! #pctGR 🔗 duke.is/pctnews20250611

📣 In this Friday's PCT Grand Rounds, Scott Garrison of UAlberta Med & Dent and Canada's Pragmatic Trials Collaborative will present the BedMed and BedMed-Frail randomized trials. Join us! #pctGR #CardioTwitter 🔗 duke.is/pctnews20250618