We are thrilled to share our new work published in Nature today reporting a long-sought peroxisomal retrotranslocation channel formed by a ubiquitin ligase complex. Phenomenal work by our postdocs Peiqiang Feng, Xudong Wu and collaborators. nature.com/articles/s4158…

Neuron vs viruses vs bacteria. Microorganisms size comparison: #biology

New preprint from the lab, and I’m super excited about this one! Our key finding? We discovered that the #nuclearreceptor PPARγ LBD and AF-1 domains physically interact! Read on for more biorxiv.org/content/10.110… 1/

3 years of testing. And I think I’ve got my technique finally down. 🥹

I had to drive to California to get this one. My clearest image of Saturn, at it's closest to Earth. Captured from the roof of a parking garage after driving all day.

This video by Alex Ritter, PhD shows an immune cell called a T cell (purple) approaching and attaching to a cancer cell (teal). The T cell tries to kill the cancer cell by secreting a toxin (red wave), but the cancer cell survives. Follow this thread to see how this battle ends. ⬇️

I found this creamer in our faculty fridge. It has been expired for almost 12 years now (!?). I don't think I can throw it away, since it definitely has tenure at this point

Here come the Gators... 🎥 The #jOURney: Trailer

HOW 'BOUT THEM GATORS BABY?! 🐊

Excited to share results on fitting protein structures to density maps with diffusion models! Our setup uses priors from language models and simultaneously predicts the structure and fits the atomic model to densities, with zero pre- or post-processing. (1/3)

Today I pointed my telescope at our sun and captured the sharpest image I’ve captured to date

BREAKING - Finally here Ian Lauer Astro & I shot this from our Alabama backyard!!! The photo shows “Abell 85”, a stunning supernova remnant.

Very glad to share our latest paper about the biosynthesis of Lyngbyastatins. Very fortunate to collaborate withDrs. Hendrik Luesch and Val Paul. Congrats to Dipesh Dhakal and the rest team. Thanks to NIH! pubs.acs.org/doi/10.1021/ac…

Brain cell vs viruses vs bacteria:

A research team, including 2021 Fellow Austin Evans FLORIDA UF Chemistry has discovered a new form of carbon that has the potential to unlock new nanomaterials - with applications in electronics, aerospace, automotive, and defense. Published nature today - schmidtsciencefellows.org/news/discovery…

New preprint with amazing result that histone-fold proteins from bacteria form a sheath around linear DNA rather than wrapping DNA around a core like eukaryotic and archaeal histones. biorxiv.org/content/10.110…

George & Rebeca here for the Sternberg Lab's inaugural tweet! We are excited to describe the reconstitution of CRISPR-associated transposases (CASTs) in human cells for programmable DSB-free insertion of large DNA cargo at genomic loci Nature Biotechnology🧬 1/8 rdcu.be/c8GWQ

If you are at the 2024 proteinsociety annual symposium, visit me at my poster tonight (Thursday) to chat about our story! (poster TH40)