GWTG-HF data shows ~80% of patients with newly diagnosed #HFrEF are eligible for #quadtherapy yet 1/6 receive it. If prescribed, rapid initiation of #GDMT at the time of HF diagnosis yields large absolute mortality reductions. bit.ly/3Mn0oq7 Gregg Fonarow MD Steve Greene #JACCHF

🔥❤️‍🔥 #FINEARTS_HF. #FineHearts_HF #Finerenone confirmed a 16% RRR of #CV ☠️ & Total #HHF 🏥 A 2nd pillar for #HFmrEF & #HFpEF has just been built 🏛️ #HFUA EJHF Editor-in-Chief NEJM Gregg Fonarow MD James Januzzi Jr MD Andrew J Sauer MD BiykemBozkurt Michele Emdin Ritu Thamman MD Sergio Kaiser MD, PhD, FACC, FESC 🇧🇷🇮🇱🇷🇴🇺🇦 bit.ly/3TdO13r

FINEARTS - HF: a win for patients with HFmrEF/HFpEF. Multi-pillar approach to treating HF>40% now clearly emerging. Earlier implementation approaches now needed to fully realize the population level benefits.

Mineralocorticoid receptor antagonists (MRAs) remain underutilized for heart failure. New data on nonsteroidal MRAs is promising for improved heart failure treatment. bit.ly/4e07BYF #JACCHF #ESCCongress #HeartFailure Andrew J Sauer MD

What a moment! The Lancet Editor richard horton and #JACC Editor Harlan Krumholz came together to celebrate the new partnership between the Journals. A rare opportunity for the two platforms to come together to improve CV care!

Beautiful venue for JACC Journals reception at #ESCCongress yesterday! Great opportunity to meet the leaders in #CVcare, Inspiring convos and thoughtful discussion. #Selfies of #ESCCongress

Happening now in Belgrade: dive into the latest breakthroughs in #hypertension drug therapies! 💊 Led by the expert chairs BiykemBozkurt and #AnthonyRodgers—! #ESCCongress

Exploring #AldosteroneSynthaseInhibition for #hypertension with Dr. Dr. Deepak L. Bhatt: 📍 #Baxdrostat: A highly selective #ASI 📍 some studies: #BrigHTN and #HALO for uncontrolled #HTN 📍 #Aldosterone plays a vital role in poorly controlled or resistant #HTN 📍 Potential ⬆️

📌Mineralocorticoid Antagonism in #HeartFailure: Established & Emerging Therapeutic Role #StateOfTheArt #MRA #HF #JACCHF

From ACC Vice President Christopher Kramer MD at #ESCCongress: CMR in #myocarditis: when should a genetic #cardiomyopathy be suspected? ⬇️ Clues: 🔍 Family history 🔍 Recurrent myocarditis 🔍 Septal or ring-like LGE 🔍 LV dysfunction bit.ly/3AAwQ5o #JACC #JACCHF #ACCBOT

New JACC Journals #JACCHF 🫀❤️‍🩹 ‼️Rapid uptitration of #GDMT ▪️⬇️ #HF-related morbidity & mortality  🌟Regardless of underlying HF risk profile DOI: 10.1016/j.jchf.2024.04.017

New in #JACCHF: REVIVED-BCIS2 showed PCI in addition to #GDMT in #ICM did not improve health status beyond 6 months compared with #GDMT alone. PCI should not be recommended for all ICM. jacc.org/doi/10.1016/j.… Editorial: jacc.org/doi/10.1016/j.…

Recognition of preshock or early CS states is important to facilitate early identification, to guide appropriate triage and to enable prompt interventions aimed at delaying or preventing the onset of overt CS. bit.ly/3zeRsQn #JACCHF Sid M. Patel TIMI Study Group

New in #JACCHF: 🔥 Obesity & Weight Loss Strategies for Patients with Heart Failure Nice review of this important target in the management of #HF JACC Journals JACC HF: jacc.org/doi/10.1016/j.…

Now in JACC Journals #JACCHF, analysis ▶️ DAPA-HF+DELIVER ✅ Pts w/ recent HFH had highest clinical risk + greatest benefit post randomization for risk reduction of worsening HF + CV 💀 Pre-discharge implementation of #GDMT more important than ever tinyurl.com/4dr6y89p

🔥🔥 ☠️ for phenotypes along preshock -> CS continuum 👉 jacc.org/doi/full/10.10… JACC Journals #JACCHF Critical Care Cardiology Trials Network 🎯 Hypoperfusion +/- hypotension -> ⬆️☠️ 🎯 normotensive CS -> distinct CS phenotype 🎯 Identify pre-& early shock to improve #CardiogenicShock outcomes

What do we know? 🏷️ CS presents with variable #hemodynamics & end-organ injury patterns 🏷️ Early intervention 🙅‍♂️frank CS & ⬆️ survival 🏷️ Implications of ⬇️ CO in absence of end-organ dysfunction not well-defined.

Critical Care Cardiology Trials Network registry data 2017 to 2023 4 groups: No end organ dysfunction- -Isolated ⬇️ CO; -HF with isolated ⬇️ BP W End organ dysfunction: -normotensive CS (MAP > 60, SBP > 90) -classic #SCAI stage C CS 2498 CICU admissions ~ above 4 definitions Stage D or E excluded

Results: No clinically meaningful differences in baseline demographics across 4 groups. End organ dysfunction- ⬆️ baseline CKD, ⬆️ SOFA scores, ⬆️ 💔 arrest Isolated low CO ~ prior h/o HF SCAI stage C ~ ⬆️ ACS

Read the insightful editorial on need for further subcategories in pre-shock by Shelley Hall Amit Alam 👉 jacc.org/doi/full/10.10…