Do you need to quantify lipid droplet-mitochondrial contact sites in hundreds of cells? Have a look to ContactJ: the automated IF method developed by Maria Calvo and Gemma Martin CCiTUB with a little help of @albertpol10 and @LabParton f1000research.com/articles/10-26…

Deux postes ouverts à la mobilité Inserm et externe au CIRI Lyon : un poste d'IE en techniques biologiques dans l'équipe de Bénédicte Py et un poste d'AI en gestion administrative. Plus d'informations sur ciri.ens-lyon.fr/ciri/news/2022… Merci de vos RT.

Our new special issue is out: #CellBiology of #Lipids. Guest edited by James Olzmann and packed with interviews, review and research articles, short reports, tools and resources and two cell science at a glance posters. tinyurl.com/yc8yzvcz

A new mechanism of viral subversion of the nuclear pore by hepatitis C virus #HCV is revealed in our newly published paper in mBio! ➡️ journals.asm.org/doi/full/10.11… CIRI Lyon 1/3

Combining biochemical assays and confocal #microscopy 🔬, we show that Nup98, a component of the nuclear pore and annulate lamellae in the cytosol, is recruited by #HCV core protein to viral assembly sites, where the concentration of +RNA genome is increased. 2/3

Notably, using 3D-SIM super-resolution microscopy in JFH1 HCVcc-infected cells, we show that Nup98 is apposed at the edges of lipid droplets covered by #HCV core protein! Nup98: green channel HCV core: red channel HCV NS5A: blue channel 3/3

Our paper is out at Journal of Cell Biology. ORP5/8 control lipid droplet biogenesis and maintenance at mito-associated membranes (MAM), via their lipid transfer activity. MAMs recruit ORP5/8, phosphatidic acid, and seipin during lipogenesis for proper LD assembly. rupress.org/jcb/article/do…

Great talks at #EMVZ in beautiful Saint-Raphaël this last few days! We were really happy to be able to present some of our work on #CCHFV, trafficking, and ISGs there. Thank you to the organizers!

Join our innovative team at CIRI in Lyon! We're seeking a passionate post-doc in immunology to lead groundbreaking research in B cell genetic reprogramming for #immunotherapy. State-of-the-art facilities and a collaborative environment await you. Apply by Dec 15! CIRI Lyon

Great seminar from Karim Majzoub today!! Thanks for sharing some exciting findings and for the storytelling 😃 #everythingaboutdelta (#andsnakes!)

Funny science can make you win prizes! Thanks to UAR Biosciences 3444 for supporting microscopy. FL Cosset's lab

🥳Exciting news for #CCHFV research! We identified and characterized trafficking motifs in Gc and Gn glycoproteins and the role of the cellular protein PACS2 in assembly of viral particles!! 👉tandfonline.com/doi/full/10.10… CIRI Lyon Bertrand Boson

A breakthrough from the lab! A game-changer and the dawn of a new era in membrane and organelle biophysics and biology. We've generated giant organelle vesicles #GOVs with conserved biochemical activity. ANR - Agence nationale de la recherche @LP_ENS_ École normale supérieure | PSL Nature Communications nature.com/articles/s4146… 1/6

Glad to see that our paper on SARS-CoV-2 virion assembly is the 3rd most cited paper of JBC within the last three years!😁 CIRI Lyon Bertrand Boson Solene Denolly

Two Engineer and post-doc positions available at the Hepatotropic & Emerging Agents Laboratory (CIRI, Lyon, France) to strengthen research on the Crimean-Congo hemorrhagic fever virus (CCHFV) . Please apply at [email protected]