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Illumina But With Nanopore: Sequencing Illumina libraries at high accuracy on the ONT MinION using R2C2 biorxiv.org/cgi/content/sh… #bioRxiv

Excited to share our Oxford Nanopore method to simultaneously sequence full-length host and viral transcripts without PCR. This is enabled by a novel RNA pre-treatment scheme we call CASPR that increases the sensitivity and specificity of cDNA generation. doi.org/10.1101/2022.0…

Delighted to take part in this new endeavor led by Vittorio Saggiomo (@[email protected]) together with other open-science makers Tobias Wenzel 👨🏼‍💻👨🏼‍🔬🧫🔬⚙️ and Mirela Alistar We've all long supported accessible microfluidic fabrication and we are dedicated to making this Special Issue, well, truly special 💜

CFU stands for "cat-forming unit"

"Head of genetics at GlaxoSmithKline: “If I was able to access a full medical history of 500k people across five African countries, and analyse genetic data, that would be a far better investment in understanding genes & disease than another 500k-person study in Europe.”

So glad to have Ana Martinez representing our iSEP-SEQ project (microfluidic #cfDNA extraction + ONT seq for sepsis dx) at Oxford Nanopore Events LC22. She's getting a lot of interest! 😍🙏

We've made a machine to help you extract the ccfDNA quickly, when you need it, where you need it! and anyone (almost) can use it 👉 Poster # 10 onsite, # 46 online

A paper from my MRes, co-1st author with ⁦Jamie McMurtrie⁩ and ⁦@DominiqueChaput ⁦@bentemperton⁩ ⁦University of Exeter⁩ ⁦@ExeterMarine⁩ showing- Relationships between pond water and tilapia skin microbiomes in aquaculture ponds in Malawi sciencedirect.com/science/articl…

Just came this morning: all our submitted abstracts are accepted at @MicroTAS22, good result! 🎉 Well done to all our staff and collaborators! To name a few Md Ehtashamul Haque Ana Martinez @JamieRylance Appan Roychoudhury EdinClinTox Till Bachmann Kazuhiro Horiba and many others Heriot-Watt Engineering & Physical Sciences

Two weeks of training here at The Royal (Dick) School of Veterinary Studies & The Roslin Institute for colleagues from Blue Resources Trust & Wayamba University of Sri Lanka. We’re using the hand-held Oxford Nanopore MinION for genetic species ID of sharks and rays! 🧬🦈 Thanks to Shark Conservation Fund & Save Our Seas for making this possible.

Our poster presentation “#Nanopore and Illumina sequencing for pathogen #metagenomics and host transcriptomics of cerebrospinal fluid in infantile central nervous system infections” at #idweek2022 in Washington, d.c. Poster number is 542.

Is that just me, or Today's poster session @MicroTas2022 was quiet? Anyway, if you want yo chat about any of our posters, please DM! 🙏 Also please admire our colour matching poster selection 🤩 #microtas2022 #microfluidics #LabOnAChip

We have developed a tool for fast extraction of microbial cfDNA, and combined it with direct nanopore sequencing - we are ready to tackle this in under 6 h! We are looking for clinical collaborators to help demonstrate the utility of our workflow in the clinic - get in touch

First to use long-read sequencing in Heriot-Watt University Heriot-Watt Research@EPS 😎✌️Amazing tech. Credit to Nick Loman and Josh Quick for inspiration, Ana Martinez for tech dev and hard work Dr. Amanda Warr 🧬 for tech/bioinformatics support Kazuhiro Horiba for bioinformatics support ..it takes a village..

I'm excited to share the first Dogstails paper (preprint), which thoroughly describes all the optimisation work we've done since 2019 to develop a rapid diagnostics and AMR prediction pipeline for canine clinical samples, using Oxford Nanopore sequencing! biorxiv.org/content/10.110…

WOULD YOU PLEASE LOOK AT THEM? These centrifuge tube holding bulbasaurs are the best! 🥰💚

The Collection of Bespoke Laboratory Equipment (COBLE) is accepted with minor revisions in #AppsPlantSci which means I can finally post our designs! Want to #3Dprint your own lab equipment? Download the designs and step-by-step instructions here! printables.com/model/45750-co…

📢JOB ADVERT: 24 months Research Associate in Molecular Biology📢 Come and develop novel techniques for the Enrichment Of Circulating Tumour DNA For Improved Cancer Treatment, with me and Nick Leslie, in our beautiful campus in Edinburgh, Scotland! RT Pls bit.ly/4b9RQNh

On a quick note from maternity leave: My group's publication on using real-time Oxford Nanopore genomics to enhance the accuracy of antibiotic resistance profiling in complex infections led by Ela Sauerborn TU München Helmholtz Munich | @HelmholtzMunich is now published: nature.com/articles/s4146…

When writing bioinformatics tools, I often need small datasets to test edge cases or invalid file formats, e.g. files that are truncated, unsorted, have extraneous whitespace, etc. I started compiling examples here: github.com/omgenomics/bio…, contributions are welcome!