Next, they pinpointed specific WHO-classified antineoplastic and immunomodulating agents that significantly heighten the risk of breakthrough COVID-19 infections. This critical insight is key for enhancing patient care alongside vaccines. 4/9

The authors identified a critical Insight: their data shows a surprising link between PD-1/PD-L1 inhibitors and an elevated risk of COVID-19 breakthrough infections. 5/9

CD20 monoclonal antibody & calcineurin inhibitors were linked to higher COVID-19 breakthrough infection rates. The authors argue this observation calls for tailored patient counseling and infection prevention strategies for patients treated with these medications. 6/9

Despite pandemic related challenges, the authors identify significantly different post-immunization cytokine profiles in patients treated with WHO classified antineoplastic and immunomodulating agents. 7/9

The authors conclude that analysis of 20,000+ patient records revealed a higher COVID-19 breakthrough infection risk in patients on certain antineoplastic and immunomodulating drugs. This is a game-changer in protecting high-risk patients! 8/9

Read the full story here: jitc.bmj.com/content/12/1/e… 9/9

Read more about our recent study looking at post #Vaccine protection against #COVID19 in individuals on immune modulating and antineoplastic agents. Read more 👇 Scripps Research Translational Institute Scripps Research Tulane Medicine Tulane Department of Medicine Eric Topol Scripps Health

A high polygenic risk score plus high consumption of sweetened-beverages linked with a 3.5-fold increased risk of atrial fibrillation ahajournals.org/doi/10.1161/CI…

📢 Interested in bench - bedside - back #FunctionNotFailure 🫀 research, cardiac metabolism, glycobiology and clinical proteomics 🧪🔬?? My lab Johns Hopkins Cardiology is looking for a talented T-32 post-doc to join us! Visit hopkinsmedicine.org/heart_vascular… and msg if interested! 🙏 re-post!

⭐️ Medical Student & Medical Resident Mentoring Event ⭐️4/6, 12p-1p ⭐️ Drs. Ravi A. Thakker, MD & Umair Khalid discuss how to navigate #ACC24 and barriers to careers in cardiology with Drs. Dr. Martha Gulati ♥️🫀❤️‍🩹🇨🇦, Melvin R. Echols, MD, FACC, FHFSA, FASPC, Modele Ogunniyi, MD, MPH, & Jason N. Katz Spread the word to your mentees!

⭐️ Is Another Degree Right For Me? ⭐️ 4/6, 2p-3p ⭐️ Drs. Dr. Rosy Thachil, Zain Asad, MD, MS, FACC FAHA, & Farinas discuss the ins/outs of MBAs, MSEds, MBMIs, & more advanced training w/Mustafa Husaini MD MBA FACC, Natalie Stokes, Emeka C. Anyanwu, MD, Tani Kahlon MD, MBA, & MedAxiom #ACC24 #ACCFIT #ACCEarlyCareer

Come catch a discussion of #SouthAsianCVD at #ACC24 on Monday April 8th from 12:45p-2p Excited to discuss with Anandita Agarwala Kulkarni, MD FACC Dinesh Kalra, MD Jaideep Salim Virani Aarti M Thakkar and others! Catch us there! OurHealth Pradeep Natarajan Douglas Drachman Ami Bhatt, MD

I’ll start with the overview and recommendations regarding Lp(a) as a risk factor #KnowLpa National Lipid Association

This JAMA Guide to Statistics and Methods article explains effect score analyses, an approach for evaluating the heterogeneity of treatment effects, and examines its use in a study of oxygen-saturation targets in critically ill patients. ja.ma/3TTXJXZ

My lab UW-Madison CRB has few positions available: Research Intern (post-bac position), Research Specialist (more senior lab tech) and Postdoc. Please check the following links or contact me if interested! hr.wisc.edu/postdoc-and-re… jobs.wisc.edu/jobs/research-…

Mind body connection? New report in JACC Journals suggests yes especially in relation to stress attenuation & physical activity in #cardiovascular benefit in 50k adults. Particular benefits seen in #depression. Read more👇 jacc.org/doi/full/10.10… #CardioTwitter #MedTwitter

So many great folks and friends in this group promoting human health, honored to be among them time.com/collection/tim… TIME TIME Health #TIME100HEALTH

We know that aerobic #exercise is good for the #heart but does time matter? Angelo Sabag et al show that evening was better than morning or afternoon with⬇️mortality, #CVD, & microvascular disease. Exercise when you can. But evenings might be better. diabetesjournals.org/care/article/4…

Our paper just out on how #AI can impute most of the 12-lead electrocardiogram critical information from just 3 leads nature.com/articles/s4174… Giorgio Quer Amitabh C. Pandey Evan D. Muse Scripps Research Translational Institute Scripps Research npj Journals

Excited of this project. Very impressive on how minimal lead #ECG data can impute a full 12 lead. Many applications for future clinical care. link👇 #MedTwitter #CardioTwitter Eric Topol Giorgio Quer Evan D. Muse Scripps Research Translational Institute Scripps Research npj Journals Tulane Medicine Tulane Department of Medicine