Alex Walker (@alexwalkerpath) 's Twitter Profile
Alex Walker

@alexwalkerpath

Postdoc with @PeterJCullen @BristolBiochem, formerly postdoc @YamauchiLab @CMMBristol and DPhil Student @fodorlab @Dunn_School. Biology 🦠🧬 and food! 🍕🥐

ID: 1157829388106391552

calendar_today04-08-2019 01:43:32

36 Tweet

205 Followers

199 Following

Dunn_School (now @DunnSchool.bsky.social) (@dunn_school) 's Twitter Profile Photo

Our virtual progress seminars continue! Last week Nandita Bodra Lea Lab talked about structural work on the complement system. Yesterday, Florian Zobel Ivan Ahel Lab discussed PARP1 and tomorrow Alex Walker (Fodor lab) tell us more about his #COVID19 research

Dunn_School (now @DunnSchool.bsky.social) (@dunn_school) 's Twitter Profile Photo

Many congratulations to all the winners at today's Graduate Student Symposium! 🏅🏅🏅 1st year poster prize: Shengpan Zhang (Sattentau group) 2nd year poster prize: @RuthKetley (Gullerova group) and Fangfang Lu (Matthew Freeman Lab) 3rd year talk prize: Alex Walker (Fodor Group)

Alex Walker (@alexwalkerpath) 's Twitter Profile Photo

We present the first structures of influenza virus polymerase bound to an essential host factor, and these give us some amazing insights into how the #flu virus replicates/adapts for new hosts! Congratulations everyone Loic Carrique Haitian Fan Jeremy Keown Jonathan Grimes

Fodor Laboratory (@fodorlab) 's Twitter Profile Photo

Socially distanced cake celebration for our @nature paper nature.com/articles/s4158… 🎉 Congratulations again to all first authors Loic Carrique Haitian Fan Jeremy Keown Alex Walker Jonathan Grimes and Ervin! #influenza #cake

Socially distanced cake celebration for our @nature paper nature.com/articles/s4158… 🎉 Congratulations again to all first authors <a href="/CarriqueLoic/">Loic Carrique</a> <a href="/haitian_fan/">Haitian Fan</a> <a href="/JeremyKeown1/">Jeremy Keown</a> <a href="/AlexWalkerPath/">Alex Walker</a> <a href="/jonathan_grimes/">Jonathan Grimes</a> and Ervin!
#influenza #cake
Fodor Laboratory (@fodorlab) 's Twitter Profile Photo

Another stunning talk from Alex Walker on how 'mutation of a Flu polymerase 3' RNA promoter binding site inhibit transcription elongation' was delievered! Great work! #IUM2020 #Influenza

Another stunning talk from <a href="/AlexWalkerPath/">Alex Walker</a> on how 'mutation of a Flu polymerase 3' RNA promoter binding site inhibit transcription elongation' was delievered! Great work! #IUM2020 #Influenza
Alex Walker (@alexwalkerpath) 's Twitter Profile Photo

New preprint alert 🚨 Our latest SARS-CoV-2 work, showing that one of the domains in the viral RNA polymerase is an enzyme involved in viral RNA capping (and this reaction is inhibited by remdesivir TP)!

Alex Walker (@alexwalkerpath) 's Twitter Profile Photo

Just out today, our contribution to understanding #SARSCoV2! We show that the viral polymerase is involved in capping the viral RNA. With thanks to Fodor Laboratory Haitian Fan Jeremy Keown Michael Knight Jonathan Grimes academic.oup.com/nar/advance-ar…

Jeremy Keown (@jeremykeown1) 's Twitter Profile Photo

Really happy to see this piece of work out. With @amandaz83411502 we structurally and functionally characterised 24 nanobodies against the 1918 influenza virus polymerase. Fodor Laboratory Jonathan Grimes STRUBIOxford Dunn_School (now @DunnSchool.bsky.social) rdcu.be/cELs3

Fodor Laboratory (@fodorlab) 's Twitter Profile Photo

In a world where viruses, scientists and llamas co-exist…. happy to share our work in collaboration with Grimes' lab, on mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies produced in llamas. Check it out! nature.com/articles/s4146…

In a world where viruses, scientists and llamas co-exist…. happy to share our work in collaboration with Grimes' lab, on mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies produced in llamas. Check it out!
nature.com/articles/s4146…
Alex Walker (@alexwalkerpath) 's Twitter Profile Photo

Ready for #NSV2022 after a cancelled flight led to an unexpected journey to Heathrow airport! ✈️ Excited to catch up with old friends and make some new ones!

Ready for #NSV2022 after a cancelled flight led to an unexpected journey to Heathrow airport! ✈️ Excited to catch up with old friends and make some new ones!
Fodor Laboratory (@fodorlab) 's Twitter Profile Photo

The tale of influenza viruses Part II: Molecular Replication, sister to its transcription-focused Part I, is now aired online in Trends in Microbiology! Click here ⬇️ to check out the most recent structural updates on influenza virus genome replication! sciencedirect.com/science/articl…

The tale of influenza viruses Part II: Molecular Replication, sister to its transcription-focused Part I, is now aired online in Trends in Microbiology! 

Click here ⬇️ to check out the most recent structural updates on influenza virus genome replication!

sciencedirect.com/science/articl…
Fodor Laboratory (@fodorlab) 's Twitter Profile Photo

Using virion vRNPs, together with purified proteins, we have, for the first time, recreated the switch from influenza virus transcription to replication, AND a full cycle of genome replication inside a test tube🧪Amanda Zihan Zhu Haitian Fan PLOS Biology ➡️journals.plos.org/plosbiology/ar…

Alex Walker (@alexwalkerpath) 's Twitter Profile Photo

Really glad to contribute to this work led by the crazy-talented (although not on social media!) Rebeka Butkovic 🎉 An exciting first step into the fascinating world of cell biology! 🧪🧫