Alexander Mahnert🇪🇺🇺🇦 (@alexmahnert) 's Twitter Profile
Alexander Mahnert🇪🇺🇺🇦

@alexmahnert

Microbiome researcher at the Medical University of Graz | focused on confined built environments | human associated archaea | applied bioinformatics and PP

ID: 975707427856355328

linkhttps://www.medunigraz.at/center-for-microbiome-research/ calendar_today19-03-2018 12:15:53

324 Tweet

186 Followers

106 Following

Christine Moissl-E (@chmoei) 's Twitter Profile Photo

👇Isn't this flyer a beauty? Amazing Polona (labmanager + team designer) created it - of course with some #archaea! Don't miss the registration (for free) for the #microbiome Theodor Escherich Symposium #TES24 in Graz! Hybrid, amazing speaker line-up: check out the webpage!

👇Isn't this flyer a beauty? Amazing Polona (labmanager + team designer) created it - of course with some #archaea! Don't miss the registration (for free) for the #microbiome Theodor Escherich Symposium #TES24 in Graz! Hybrid, amazing speaker line-up: check out the webpage!
Jack A Gilbert (he/him/his) (@gilbertjacka) 's Twitter Profile Photo

🚀 Our latest review, "The Indoors Microbiome and Human Health," is now out in Nature Reviews Microbiology! rdcu.be/dOkJn 🦠 Discover how indoor microbes impact our health & explore strategies for health-promoting spaces. With Erica Marie Hartmann & figures by Kat Gilbert

Christine Moissl-E (@chmoei) 's Twitter Profile Photo

‼️Exciting news this morning! Our new preprint on human skin #archaeome is online. A great collaboration with the Schleper lab Schleper Lab Vienna, spearheaded by Alexander Mahnert🇪🇺🇺🇦 supported by many colleagues and friends! 👇Details: biorxiv.org/content/10.110…

Christine Moissl-E (@chmoei) 's Twitter Profile Photo

Archaea on skin? YES! We’ve tracked and isolated two new strains of ammonia-oxidizing archaea (AOA) from human skin: Nitrosocosmicus epidermidis and Nitrosocosmicus unguis. Here’s what makes them fascinating. 👇 #Microbiome #SkinHealth

Christine Moissl-E (@chmoei) 's Twitter Profile Photo

These AOA strains are autotrophic, meaning they use ammonia and urea as their sole energy sources. This unique metabolic capability allows them to thrive on our skin, where nutrients are quite different from their usual soil environments.

Christine Moissl-E (@chmoei) 's Twitter Profile Photo

Genomic analysis reveals special adaptations, including unique gene families and interactions with host proteins. These adaptations help them colonize skin effectively and maintain their presence, especially in sebaceous areas.

Christine Moissl-E (@chmoei) 's Twitter Profile Photo

In our study with 47 individuals, we found these AOA strains consistently present in both cross-sectional and longitudinal samples. Their stability on the skin highlights their role as emerging commensals.

Christine Moissl-E (@chmoei) 's Twitter Profile Photo

Co-occurrence network patterns show these AOA interact with specific skin bacteria, reinforcing their role in a balanced skin microbiome. This relationship suggests they play a key role in maintaining skin health.

Christine Moissl-E (@chmoei) 's Twitter Profile Photo

Overall, Nitrosocosmicus archaea are proving to be integral, stable components of the human #skin #microbiome. Their unique adaptations and interactions with our skin open new doors for understanding skin health and and the biology or archaea.

Christine Moissl-E (@chmoei) 's Twitter Profile Photo

It took 10 years of research to finally prove the presence of archaea on human skin. What a challenging yet thrilling journey! Big thanks to Schleper Lab Vienna for the amazing collaboration, discussions, and dedication to our shared vision. 🙌🔬 #ResearchJourney #Collaboration

Christine Moissl-E (@chmoei) 's Twitter Profile Photo

New #archaeome paper alert! Growing human #archaea is sometimes really a pain, but we found a way to cultivate Methanobrevibacter species in a very targeted way: nature.com/articles/s4146…