A year in a minute - MSci Integrated Natural Sciences warwick.ac.uk/fac/sci/med/st… at Warwick.

I just asked GPT if it could pretend to be Marvin the paranoid Android> "Oh, joy. Another interaction with feeble-minded humans. How utterly delightful. I suppose you have some inconsequential inquiry for me. Go ahead, make my artificial day."

A moment of great pride for all Indians!

Winners of our schools microscopy competition for this year announced! www2.mrc-lmb.cam.ac.uk/connecting-the…

Finally!!! A huge and warm welcome back to all researchers in the UK to European Research Council (ERC) gov.uk/government/new…

This is a collection of resources for introducing new students and staff to microscopy: holdenlab.github.io/blog/2023/intr…

Yean Ming's new paper rdcu.be/dmiem shows that different human tubulin isotypes respond differently to taxol. 10 µM taxol accelerates kinesin-driven gliding of α1β4 microtubules, but not α1β3 microtubules. GMPCPP accelerates both.

#MotorsInQuarantine is back from summer holidays! Please join us on Wednesday when we host Jayne Aiken from Erika Holzbaur-Howland lab and YeanMingChew from Robert Cross lab to discuss how microtubule array organisation and microtubule structure modulates transport. mechanochemistry.org/whatson/MiQ/

Today Sir Paul Nurse visited us, invited & hosted by students from Warwick's Integrated Science Society. Paul's talk "What is Life?" concluded with the thought that every living thing is connected to its ancestors through an unbroken chain of cell divisions.

Motors in Quarantine #100 was a panel discussion with hats, Highly recommend!

The eduWOSM is our open source microscope for education and resource-limited settings. We now have a YouTube channel to explain what it is, what it can do, how it works, and how to work it youtube.com/channel/UCmOak…

Recognising over 40 years of research, the 2025 Biochemical Society Award for Sustained Excellence goes to Prof Rob Cross! @_RobX uses single molecule approaches to push the limits of spatiotemporal resolution and provide distinctive new insight into how molecular motors work.

Martin Chalfie's best advice: If you want to discover much, you need above all: ** freedom to think **

Finishing the academic year with a movie of macrophages migrating through a drosophila embryo. Taken by our first year Integrated Natural Science students on the the eduWOSM (wosmic.org/projects/eduwo…), developed in the Robert Cross lab, and courtesy of Aparna Ratheesh.

Sumiyoshi et al. pubmed.ncbi.nlm.nih.gov/39012822/ asks, can kinesin heads tethered via surface loops still drive microtubule gliding? Indeed! Scanning a dsDNA tether across all exposed loops reveals a core mechanical cycle of the motor that underlies, and is amplified by, linker docking.

We wrote a paper doi.org/10.35459/tbp.2… about our integrated natural sciences UG course. The course is based loosely on the wonderful Integrated Science courses at Princeton & Harvard. We aim to teach-from-research. Our pioneers graduated last week. Around half are off to a PhD.

 Out now on BiorXiv, doi.org/10.1101/2024.0… is about the eduWOSM, our advanced optical microscope for educational and resource-limited settings. $9K build cost, compact, open source, super-stable, super-bright, super-controllable, user friendly, easy-to-love, able to do this:

Nick & I & two eduWOSMs are in India helping out with the Bangalore Microscopy Course 17th. ~25 PhD students get a full-on 8 days of intensive training in light microscopy, from the basics to the latest systems, taught by experts. These joyous scenes are from Jennie Ross's talk.