Membranoproliferative glomerulonephritis (MPGN) can be divided into immune-complex MPGN (IC-MPGN) & C3 glomerulopathy (C3G). Read this Original Article on clinical characteristics & outcomes of IC-MPGN & C3G in Japanese children. #OpenAccess
link.springer.com/article/10.100…

Congenital anomalies of the kidney and urinary tract (CAKUT) represent a frequent cause of pediatric kidney failure. CNV genomic variations can also affect miRNA regions. Read this Original Article on cCNV-miRNAs & CAKUT occurrence & expressivity.
link.springer.com/article/10.100…

French pediatrics, inside & outside the hospital, is in crisis: lack of beds, transfers, degraded procedures, deprogramming of “non-urgent” care, etc. Read this Editorial Commentary on the consequences of paradoxical injunctions & a plea for action.
link.springer.com/article/10.100…

Read this Original Article that evaluates parenting stress, anxiety, & depression symptoms & their associated factors in parents of children w/chronic kidney disease (CKD).
link.springer.com/article/10.100…

Limited data exist re the clinical course & outcomes of children w/primary focal segmental glomerulosclerosis from low- & middle-income countries. Read this Original Article on kidney outcomes in children w/primary FSGS from a low- & middle-income country.
link.springer.com/article/10.100…

Children w/anti-neutrophil cytoplasmic antibody-associated vasculitis benefit immensely from avacopan as it reduces steroid use. Read these Clinical Insights in a case of rapid avacopan-induced liver injury in pediatric granulomatosis w/polyangiitis.
link.springer.com/article/10.100…

Children w/nephrotic syndrome are at risk of obesity & growth impairment from repeated steroid treatment. Read this Original Article on risk, timing, & predictors of obesity & short stature among children w/nephrotic syndrome.
link.springer.com/article/10.100…

Atypical hemolytic uremic syndrome (aHUS) is an ultrarare disease affecting about 2 cases per 100,000/yr; children comprise 0.26–0.75 cases per 100,000. Read this Editorial Commentary on the need for testing for anti-FH antibodies in all children w/aHUS.
link.springer.com/article/10.100…

Between 5-50% of atypical hemolytic uremic syndrome (aHUS) cases in children are caused by autoantibodies against complement factor H (CFH). Read this Original Article on anti-FH antibody-associated HUS treated with eculizumab.
link.springer.com/article/10.100…

Acute post-streptococcal glomerulonephritis (APSGN) is the most common glomerulonephritis in children; clinical presentation varies widely. Read these Clinical Insights on an atypical manifestation of APSGN in an 8-yr-old girl.
link.springer.com/article/10.100…

Children w/CKD are vulnerable to dehydration. Read this Review of risk factors & consequences of mild dehydration & underhydration in CKD, w/a focus on risk of CKD progression. Mia (Amelia) Le Page #OpenAccess
link.springer.com/article/10.100…

Read this Original Article on early diagnosis of congenital solitary functioning kidney (SFK) & risks of unilateral kidney agenesis (UKA) & unilateral multicystic dysplastic kidney (UMCDK). #OpenAccess
link.springer.com/article/10.100…

Recombinant human growth hormone therapy is routine for children w/CKD who are exhibiting growth impairment. Read this Review of the multisystem effects of growth hormone therapy in pediatric patients w/CKD & areas where additional research is needed.
link.springer.com/article/10.100…

Clinical practice guidelines do not address many scenarios in patients w/systemic lupus erythematosus (SLE). In some countries patients lack access to biologics. Read this Educational Review of options for initial treatment of nephritis in patients w/SLE.
link.springer.com/article/10.100…

Acquired cystic kidney disease (ACKD) can occur in patients w/CKD & kidney failure, & its incidence increases w/dialysis duration. Read these Clinical Insights on prevalence of ACKD in children.
link.springer.com/article/10.100…

Most studies of patient outcomes re Shiga toxin-producing Escherichia coli-hemolytic uremic syndrome (STEC-HUS) focus on kidney status at last assessment. Read this Original Article on kidney function changes during follow-up & long-term kidney outcomes.
link.springer.com/article/10.100…

In pediatric kidney failure, native kidneys may pose a risk to successful transplant outcomes. Read this Review of indications for native nephrectomy & current knowledge gaps; plus, a surgical perspective re timing & approach. Free access this month.
bit.ly/43XLu1z

IgA nephropathy is a genetically complex multifactorial trait. Over the past decade, population-based genome-wide association studies have identified >30 IgAN risk loci. Read this Review of the state of genetic research in IgAN.
link.springer.com/article/10.100…

Medication nonadherence is a barrier to HT control. The CDC recommends 90-day fills yet antihypertensives are often dispensed as 30-day fills. Read this Original Article on fill duration in pediatric HT, adherence, & disparities.
link.springer.com/article/10.100…

HUS may cause AKI in children. Patients may present w/kidney abnormalities years after HUS recovery. Read this Original Article on the long-term outcome of Shiga toxin-producing Escherichia coli-associated HUS in pediatric patients. #OpenAccess
link.springer.com/article/10.100…