Accelerated iTBS = 10 TMS sessions/day over a wk. It is powerful for treatment resistant #depression (FDA approved=SAINT). Here is its first sham-controlled trial in treatment-resistant #bipolar depression: ncbi.nlm.nih.gov/pubmed/38985492 Benefits were large, but trial was small (24)

Reassuring news for #benzo d/c in study of 73 older adults: ncbi.nlm.nih.gov/pubmed/38952209 Sleep= initially worse after stopping, but stabilized by 3 mths Depression= improved after a year off #benzos; worry unchanged Limitation= Uncontrolled, high drop-out #anxiety #psychiatry

John G. Luehr et al. report a pragmatic accelerated rTMS protocol for depression in a letter to the editor. The trial achieved a 70% response rate and 55% remission after just 36 sessions, without involving any MR based targeting brainstimjrnl.com/article/S1935-…

Next generation #TMS delivery team… stay tuned

The value of ‘wasting time’ on deep thinking is often overlooked in a scientific ecosystem increasingly tainted by Wall Street’s productivity mindset. nature.com/articles/d4158…

Hot off the press, work led by Stefan Lang, MD PhD and his group: Non-Motor Effects of Low-Frequency Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson’s Disease: A Systematic Review karger.com/sfn/article-ab…

Fellow neuromodulation enthusiasts; lately, I have preferred to refer rTMS protocols as low- or high-frequency rather than the inhibitory/excitatory description. Now, how do you go about describing iTBS vs cTBS protocols?

In patients with treatment-resistant depression, switching to #TMS is 2.5 times more effective strategy than keep cycling through pharmacological options - a multicenter randomized controlled trial: psychiatryonline.org/doi/10.1176/ap…

Mohammad Daneshzand at al presents a model-based navigation (MBN) tool for transcranial focused ultrasound, improving targeting of the amygdala & thalamus. MBN enhances acoustic dose by 8-67%, ensuring precise, individualized treatment. brainstimjrnl.com/article/S1935-…

Viewpoint discusses why it is important for psychiatry residency programs to continue to prioritize the training of psychiatrist-scientists. ja.ma/46Dnl1q

Theta-burst stim (TBS) is used to treat depression, but how does it work? I dug into this question in my research yr with Corey Keller Angelique C Paulk, now out in Nature Communications, finding that TBS can produce plasticity-like changes in just minutes of stim. nature.com/articles/s4146…

Data continue to accrue supporting the benefit of #TMS for #bipolar #depression. UBC Department of Psychiatry VCH Research Institute Djavad Mowafaghian Centre for Brain Health. We are just one pivotal trial away from FDA indication? Fast depressive symptoms improvement in bipolar I disorder after Stanf... sciencedirect.com/science/articl…

#Antidepressant responses in #depression plateau at higher dose in network analysis of 160 trials: pubmed.ncbi.nlm.nih.gov/38902199 Exceptions? tricyclics, reboxetine in this study. Also, in earlier studies, MAOIs, venlafazine, desvenlafaxine, vortioxetine. #psychiatry

Tour the force lead by Chuck Lynch today in @nature. fMRI identifying a stable feature associated with depressive syndrome. It was great to be part of this :) nature.com/articles/d4158… UBC Department of Psychiatry Djavad Mowafaghian Centre for Brain Health UBC Medicine UBC Media Relations

Happy to share that our work applying precision mapping to individuals with depression sampled longitudinally over an extended period has been published this week in @nature. Brief recap of the main findings and their potential implications below. nature.com/articles/s4158…

I both prescribe and reduce prescriptions - whichever, to my knowledge, is best for that particular patient. Not what might make me feel better. I also reluctantly take medication as it seems to keep me well. Not to make my psychiatrist feel better.

Our latest publication: Metaanalysis of Repetitive Transcranial Magnetic Stimulation (#rTMS) Efficacy for #OCD Treatment: The Impact of Stimulation Parameters, Symptom #Subtype and rTMS-Induced Electrical Field mdpi.com/2950514 #mdpijcm #NIBS #TMS

Methohexital seems to have advantages over propofol in cardioversions as well. This work has implications for neuromodulation in #Canada ahajournals.org/doi/epub/10.11…

We’re grateful to ⁦Focused Ultrasound Foundation⁩ for helping us host a workshop charting the course of focused ultrasound in psychiatry, a rapidly growing field. Read our white paper here and looking forward to the second edition in 2026! ⁦Ben Davidson⁩ fusfoundation.org/posts/focused-…