1/4 Excited to share #DIISCO 🪩, a Bayesian method for inferring cell-cell interactions over time in longitudinal #singlecell data 😱 DIISCO takes in cell type proportions and receptor-ligand expression and outputs cell state dynamics and cell-cell interaction networks! 🕺💃

Come join us Columbia University's Zuckerman Institute on May 17th for the 2024 New York Area Population Genetics Meeting. Keynotes by Lindy McBride and Cedric🧬➰🧬Feschotte Register here zuckermaninstitute.columbia.edu/new-york-area-…

.Allen Institute could you point me to the right person/place to get access to the raw (fastq/bam) human cortex Smart-seq2 from portal.brain-map.org/atlases-and-da… ? Not seeing any leads on the website or forum. Thanks!

rofl like who has time to discern which of these Modern Alternatives (TM) is best to use for their python project 🧐

Vince Buffalo xkcd.com/1987/

The fantastic Machine Learning in Compbio #MLCB2023 papers are up at proceedings.mlr.press/v240/. Thanks Neil Lawrence & PMLR! We have talk recordings too at youtube.com/@mlcbconf/.

Congratulations to TatsuhikoNaito (postdoc co-mentored w/ David A Knowles (@davidaknowles.bsky.social) ) for being awarded a BrightFocus Foundation Fellowship! His project uses deep learning to predict RNA splicing from #Alzheimer's whole genome sequencing data. #ADSP #AI #ML.

#MLCB2024 will be Sept 5-6 as a hybrid event in Seattle (nice time to be in the PNW!) with a great lineup of keynotes from Ava Amini, Maria Chikina, Jian Zhou and Nilah Ioannidis. Registration is free and submission deadline is June 15th. More deets at mlcb.github.io.

🚨New lab preprint! 🚨 A deep dive to shed light on a long-standing controversy with RNA-targeting CRISPRs: Do they have high levels of collateral (trans) cleavage of other RNAs in the cell ✂️✂️✂️ — or not? New work from talented PhD student #SydneyHart & others in our lab. 📰

Thrilled to be co-chairing the inaugural #Alzheimer’s Gordon Research Conferences from June 22-27, 2025. This conference will delve into #AI/#ML, #omics, stat. genetics, fungen, sysbio, #neuroimaging, & other topics. Outstanding lineup of speakers and registration will open soon. Stay tuned!

Thrilled to finally announce that I will be starting as an Assistant Professor at the University of Pennsylvania Perelman School of Medicine this fall! I will be in the Division of Informatics Dept. of Biostatistics, Epidemiology & Informatics with a secondary appointment in the Department of Genetics Penn Genetics

MLCB2024 submissions are open at cmt3.research.microsoft.com/MLCB2024/! Deadline 6/15, more details at mlcb.github.io. Please RT!

#MLCB2024 deadline extended to June 17!!

📢I am elated to share that I will join the Center for Neural Science & Dept. of Psychology at NYU as an Assistant Professor in Sept 2025! My lab will use the remarkable food-caching behavior and active vision of chickadees to study the neural basis of episodic memory 🕊️🧠👀🏙️✨

Looking forward to #MLCB2024 later this week! Really happy to see the wide variety of work being done. Sometimes, in the past, it seems like the field converged on the same set of problems... Sad that I won't be able to be there in person this year. :(

#MLCB2024 will be streamed live from YouTube this week (Thursday and Friday). Get the link from here: mlcb.github.io

Two Troyanskaya Lab alums — Jian Zhou & Maria Chikina — giving keynotes at #MLCB2024! Jian now talking about sequence basis of transcription initiation in the human genome. Tomorrow, Maria is talking about biophysically interpretable sequence to function models.

#MLCB2024 is live at youtube.com/live/GflTIcI5i… ! First up Jian Zhou on interpretable DL for transcription initiation.