We developed ML-based software for finding cryptic sites. We applied the method to 3 proteins: two from SARS-CoV-2, and one from yersinia pestis. Thanks to everyone who contributed to the project! The preprint is available at disq.us/t/3v1sacp

#BPS2021 is now underway... I'm excited to hear about the latest work from Remy Yovanno, shown in a Thursday 11:15-11:30 talk "Role of D-Serine Binding To The NMDA Receptor Ligand-Binding Domain". Having seen some of the data, I can assure you it's worth attending!

Stephen Fried JHU's first foray in structural bioinformatics is out on GitHub. Great work by new grad student, Edgar p. Manriquez. DomainMapper annotates protein domain structure, and properly labels non-contiguous, insertional, and circularly permuted domains. github.com/FriedLabJHU/Do…

So excited to share our lab’s newest paper with Furukawa Lab CSHL, including some of my thesis work using MD simulations and network modeling to study Fab binding to the NMDAR. Thankful to have worked with such an amazing team!

New preprint from the Lau Lab and Furukawa Lab CSHL. We used molecular dynamics simulations and electrophysiology (Tsung-Han Chou) to study the role of D-serine binding to NMDAR LBDs.

The Program in Molecular Biophysics Johns Hopkins University is finally on Twitter! Follow us for news about our terrific graduate students and faculty. You can find out about our Ph.D. program at pmb.jhu.edu . Please follow and RT!

In 2020 I got a CNC machine for woodcarving. I recently discovered how to carve protein structures. It’s fun when an unrelated interest intersects with my work! (I chose ubiquitin as a test case b/c it’s small and well-known. The carving process should work for most proteins.)