Un texto a modo de homenaje a nuestro compañero Manolo, que nos dejó inesperadamente en esta semana. Un magnífico científico, entusiasta y humanista que siempre estará en nuestro recuerdo. ➡️i.mtr.cool/wiugmggszh

» Genomic landscape of antiviral defense systems in prokaryotes and phages | bioRxiv biorxiv.org/content/10.110…

AlphaBridge: tools for the analysis of predicted macromolecular complexes biorxiv.org/cgi/content/sh… #biorxiv_bioinfo

AlphaBridge: tools for the analysis of predicted macromolecular complexes • AlphaBridge introduces tools to analyze and visualize the interfaces between predicted macromolecular complexes using data from AlphaFold3. It processes the predicted interactions into intuitive

Funded PhD available with us, Martin Llewellyn and James Cotton UofG Sii UofG SBOHVM Centre For Parasitology to study genome replication and (in)stability across diverse kinetoplastids. Applications (via FindaPhD) taken from Nov 1st - Jan 12th. Enquiries welcome. tinyurl.com/mfz4yh3k

Excited to share our first DNA-protein work! Thanks to Mahipal Ganji for collaboration and the encouragement to explore this system and ARNAB CHATTERJEE for the help during revision! Cryo-EM Reveals the Mechanism of DNA Compaction by Mycobacterium smegm... sciencedirect.com/science/articl…

We have a post-doc opportunity for a molecular microbiologist available. Please contact directly for an informal discussion. jobs.ac.uk/job/DKH037/res…

Excited to share our last collab paper in Nature Communications on the structure & interference mechanism of the mysterious 𝗧𝘆𝗽𝗲 𝗜𝗩-𝗔 𝗖𝗥𝗜𝗦𝗣𝗥-𝗖𝗮𝘀 system!! 🧬🚀 🔗nature.com/articles/s4146… 🧵 by @patrick_pausch below!

New from me and a huge cast of amazing bioimage analysts in J Cell Science - - "The crucial role of bioimage analysts in scientific research and publication" journals.biologists.com/jcs/article/13… . Hop into 🧵to learn more! (1/x)

Tubulin-like proteins CetZ1 and CetZ2 coordinate cellular morphogenesis in the archaeon Haloferax volcanii biorxiv.org/cgi/content/sh… #biorxiv_micrbio

RepeatsDB in 2025: Expanding Annotations of Structured Tandem Repeat Proteins on AlphaFoldDB @NAR_Open • The 2025 update of RepeatsDB vastly expands the database’s coverage, adding over 34,000 new protein sequences from more than 2,000 species, representing a fifteenfold

AlphaFold 2, but not AlphaFold 3, predicts confident but unrealistic beta-solenoid structures for repeat proteins biorxiv.org/cgi/content/sh… #biorxiv_bioinfo

🔥JOB ADVERT🔥 Looking for a postdoc to work on #machine_learning classification of #knots & #proteins and discovery of new topological invariants. Start by November 2025 Duration 2 years min Where: TAPLab Physics Astro @ Edin Generously funded by The Leverhulme Trust Retweet pls ❤️

New PhD position! Interested in using cutting-edge biophysics? 🔬Join Chris H. Hill, Dr Purba Mukherjee and I University of York to explore the mechanisms of genome replication in enteroviruses. 🧬 Apply now! 👇 tinyurl.com/573nctrh DiMeN DTP York Biomedical Research Institute Biology at York UoY School of Physics, Engineering and Technology

Why did some groups of genes get progressively closer on the chromosome  to ultimately form operons ? We addressed and quantified the role of gene multiplicity (strictly connected to the number of active replication forks in a cell) and metabolic homeostasis in this process.

» DNAproDB: an updated database for the automated and interactive analysis of protein–DNA complexes | Nucleic Acids Research | Oxford Academic academic.oup.com/nar/advance-ar…

Congrats to Dr Dave Mark on publishing his PhD work! Nicholas Tucker Microbiology Society Chromosome architecture as a determinant for biosynthetic diversity in Micromonospora - go.shr.lc/4fwg5HU

» A widespread phage-encoded kinase enables evasion of multiple host antiphage defence systems | Nature Microbiology nature.com/articles/s4156…

biorxiv.org/content/10.110… BORGS - the large extrachromosomal elements of anaerobic methane-oxidizing archaea are likely viruses and have evolved genomic features similar to Giant Viruses!

Protein layers protect #microbes from harsh environment and #viruses. A study of a sheath-forming #proteins revealed their huge diversity in #archaea and potential for involvement in cell interactions and lysis. Simonetta Gribaldo The ISME Journal ISME - International Society for Microbial Ecology academic.oup.com/ismej/advance-…