Timely publication of this special issue on the first day of #MIKIW2024! pubs.acs.org/doi/10.1021/ac…

The #HarkiLab (current and alumni) at #MIKIW24!

🚨 APOBEC3B (A3B) is a major source of🧬mutation in cancer The active site is like Teflon (not much binds) BUT Ozlem Dmr discovered a druggable allosteric site 👀 Experiments by Dan Harki Katherine Jones The Harris Lab 💪 biorxiv.org/content/10.110…

Our chemical synthesis of PTM-modified MYC peptides and their interactions with the tumor suppressor Bin1 is online Chemical Science. Congratulations @elysetwilliams, @rebeccabev5, Oliver Zerbe, and everyone else involved! 🎉 pubs.rsc.org/en/content/art… #MyFirstChemSci

At this spring's Cheers to U! Gratitude Celebration for donors, attendees heard from P4 student Ayan Mohamed; University of Minnesota Medicinal Chemistry grad student Caitlin Lichtenfels; & Dan Harki about how philanthropy has helped their respective journeys. View more photos ▶️ bit.ly/3wr5w83

Group lunch in honor of Emma Smith's last day in the #HarkiLab. Emma will be starting graduate studies Yale Chemistry in the fall. Good luck Emma!

Besides the terrific list of speakers, the overall amazing science, and the unique chance of networking, another reason to attend the EFMC #EFMCISMC24 in Rome is... Rome! efmc-ismc.org

Excited to see you all at the American Chemical Society National meeting in Denver! We have some fantastic programming for you and we hope you will join us for our social activities too! #Networking on Sunday (5-7pm), and the #HallofFame reception Tuesday evening!

The MEDI Executive Committee is here at the American Chemical Society meeting. We have some fantastic programming coming for this meeting and look forward to meeting with you all, and listening to some great science!

MEDI have started the #ACSFall2024 meeting off strong! We recognized the travel award winners at the Business Meeting on Sunday, and have had full rooms for our technical sessions. Looking forward to seeing you all over the course of the week!

📣Starting Session 10: “Computational Chemistry and Computational Biology in Drug Discovery” in Room Pantheon chaired by Dr Marco DE VIVO with a lecture from Prof. Rommie AMARO on “Computational Microscopy of Viral Targets for Drug & Immunogen Design” #EFMCISMC24 #MedChem

Excited to announce the start of EFMC-YMSC! A special thanks to Prof. Roberto Di Santo for his incredible effort in organising this incredible event, bringing together young scientists from across Europe. Thanks to the entire committee for making this possible! #EFMCYMSC

At WMIS WMIC next week, Penn Medicine’s Dr. Sunil Singhal will share clinical research that shows how enhanced tumor visualization may benefit surgeons and patients during #lungcancer surgery. Learn more here: bit.ly/4e1KZHw #WMIC2024 #tumorvisualization #meded #MedX

Join us for the @ClinicPharmSTL Research Seminar feat. Dan Harki from University of Minnesota Medicinal Chemistry. 📆 Oct. 10 @ 1p 🔬Chemical Strategies for Regulating DNA-Interactive Proteins: Targeting APOBEC Cytosine Deaminases & the N-Myc Transcription Factor 📍UHSP - ARB - Rm 449 anesthesiology.wustl.edu/events/event/c…

The MEDI strategic planning session has been a huge success! We can't wait to share with you all our plans for the future of MEDI!

New publication from the #HarkiLab: A selective Aurora kinase A degrader that elicits N-Myc degradation in pediatric neuroblastoma. Thanks to everyone involved in this project! University of Minnesota Medicinal Chemistry UMN Department of Chemistry Masonic Cancer Center, University of Minnesota sciencedirect.com/science/articl…

Online now! Targeting N-Myc in neuroblastoma with selective Aurora kinase A degraders by Jian Tang, Dan Harki, and colleagues at University of Minnesota Medicinal Chemistry University of Minnesota UT Health San Antonio HHMI UC San Diego dlvr.it/THDH9Y #chembiol

Targeting N-Myc in neuroblastoma with selective Aurora kinase A degraders by Jian Tang, Dan Harki, and colleagues at University of Minnesota Medicinal Chemistry University of Minnesota UT Health San Antonio HHMI UC San Diego dlvr.it/TJ6WS4

Thanks C&EN (Chemical & Engineering News) for the highlight! cen.acs.org/acs-news/acs-m… via C&EN (Chemical & Engineering News)

Take a look at recent work from Jared J. Anderson and Dan Harki on the identification of a novel allosteric binding site on the catalytic domain of NF-κB inducing kinase (NIK)🔥⬇ pubs.rsc.org/en/content/art… 📍 University of Minnesota