Nature research paper: Durable and efficient gene silencing in vivo by hit-and-run epigenome editing go.nature.com/3v094NP

Excited to share our review paper in Cell! With Sasha Gusev Sohini Ramachandran Yang I Li we discuss the genetic and molecular architecture of human traits, future opportunities and challenges and ways forward. authors.elsevier.com/a/1igrbL7PXqPfU

Excited to share our review paper in Cell! With Sasha Gusev Sohini Ramachandran Yang I Li we discuss the genetic and molecular architecture of human traits, future opportunities and challenges and ways forward. authors.elsevier.com/a/1igrbL7PXqPfU

This great article from Florian Markowetz sets out why almost all models fail to be translated into the clinic and suggest solutions. The same arguments apply to all clinical #genomic tests and associated #bioinformatics. A thread on my own experiences. nature.com/articles/s4169…

Happy to share our recent review about epigenetic memory! Congrats to Mencia Espinosa-Martínez María Alcázar Fabra! We hope this review is useful for some of you! And thanks to reviewers, editors and Science Advances for helpful feedback, and featuring it on the cover!

Today is a very exciting day to see this paper finally published in Nature Genetics 💫 Congratulations to Ana Topf and Volker Straub for the hard work and the resilience 👩‍🔬 🔬 👨‍🔬 JWMDRC Newcastle University Ana Topf Enjoy the reading nature.com/articles/s4158…

Our 3-year #postdoc vacancy supported by the NWO Funding is open for a few more days! Will you come work with us at Maastricht UMC+? 🧡 #bioinformatics #research #genomics #epigenomics #forensics #MaastrichtUMC

We know the importance of subtle gene dosage variation, and yet the main tool of molbio is gene KO/KD. In our new preprint, Júlia Domingo introduced subtle modulations of transcription factor dosage by CRISPRi/a, and quantified responses by scRNA-seq. 1/ biorxiv.org/content/10.110…