We report the first #cryoEM structures of #LRRK2 bound to type-1 and type-2 kinase inhibitors. Great team effort to advance Parkinson’s Disease therapeutics research! #StefanKnapp __as_n_ Kinas_s Marta Amalia Villagran-suarez Verena Dederer Aligning Science Across Parkinson’s biorxiv.org/content/10.110…

So I made a 🔵☁️ account! Find me there with same handle D. Alexander Stevens

Huge congratulations to Keren Lasker on receiving the Moore Inventor Fellowship! So excited to be working on this project, stay tuned for some incredible science 🧪👨‍🔬

🌟 Join us at Scripps Research as a faculty member! 🧪 Seeking innovative scientists utilizing structural, computational, or biophysical methods to unravel biological mysteries. Apply by Dec 1 🗓️. 🌈 Committed to diversity, we welcome varied backgrounds. Let's explore together!🚀

Was very cloudy in San Diego during the eclipse but a small break in the clouds allowed me to catch a glimpse! #SolarEclipse #SolarEclipse2023 #AnnularEclipse

New work from our Aligning Science Across Parkinson’s team: nature.com/articles/s4159…. Parkinson’s disease-linked LRRK2’s closest relative, LRRK1 is tightly regulated via different mechanisms than LRRK2. Great collaboration with Andres Leschziner, Matt Daugherty, and Knapp labs

We are looking for motivated people to join our group as #postdocs to work on the structural biology of #Parkinsons. We’re a #cryoEM lab focusing on #LRRK2. Please repost! andres-leschziner.squarespace.com

We're recruiting one or two postdocs to work on subjects at the intersection of basic research on phage-bacterial coevolution and phage therapy. Please email ([email protected]) if you're interested.

📽️ Gilliam Fellow Donté Alexander Stevens spent his time at UC San Diego searching for undiscovered mechanisms viruses use to hijack a cell’s internal transport system. Recently, he shared with HHMI how he overcomes roadblocks. ⬇️

Happy to share our lab's first preprint! We found that ER tubules hitchhike on Rab6-marked vesicles. Proud of grad student Ally Langley, lab tech @AbelingSarah and undergrad Erinn Wagner CMB @ UVM UVM Larner Med

Excited to be part of the 2024 JCC Fellows class! Looking forward to building community with this group of amazing scientists.

Huge congrats to the incredibly talented D. Alexander Stevens for becoming a @JCChildsFund fellow! Super well-deserved! Stay tuned for the amazing science Alex is working on! 🔥🚀 #ProudPI

🚀 Thrilled to join the @LoulouFoundation family! 🌟 Stay tuned for exciting science led by our incredibly talented postdoc, Andrea Colarusso. Exciting times ahead!

🔬The Fritz-Laylin lab is hoping to hire a microscope specialist in the fall of 2024. We are seeking someone with experience in light microscopy and quantitative image analysis. EM experience would be a plus! If you are interested, please send me your CV and a cover letter.

Excited to share our new preprint describing the role of Lis1 in regulating dynein's mechanochemistry and activation. Kendrick Nguyen Eva Karasmanis Samara Reck-Peterson Andres Leschziner biorxiv.org/content/10.110…

Honored to be named a 2025 HHMI Hanna Gray Fellow! Grateful to Keren Lasker for her mentorship and enthusiastic support and to Scripps Research for the incredible and inspiring intellectual environment. Excited for the journey ahead! #HannaGrayFellows

Tetanus on demand! (not for bioweapons, but for neuroscience research) Tetanus toxin induces paralysis by using a protease to cleave VAMP2, a protein required for synaptic vesicle fusion and neurotransmitter release. To harness this toxicity and use it as a beneficial tool for

I am excited for this opportunity to chair the Department of Biochemistry and Biophysics at Weill Cornell Medicine! news.weill.cornell.edu/news/2025/01/d…

Honored to be included among such an inspiring group of scientists!