Exited to announce the publication of our work showing that activated type I Thoeris SIR2 effector ThsA forms helical filaments in nature. Thread below nature.com/articles/s4158…

Our take on Thoeris type I system. Glad to see these right-handed spirals in (N)nature. 🧬 This work was led by Giedre Tamulaitiene (Giedre Tamulaitiene) in collaboration with Sorek Lab. nature.com/articles/s4158…

More details on the discovery, led by super talented Ilya Osterman, are in the thread below x.com/SorekLab/statu…

Our NAD-reconstitution story is finally published in nature rdcu.be/dU5AQ Thank you to all co-authors, especially to hadarsamra, @FrancoisRousset, Elena Loseva, Erez Tzvi Yirmiya, Adi Millman, and everybody in the Sorek Lab for their help and support.

Registration for our PhD / postdoc course 'Fundamentals of Basic and Applied Phage Biology' is now open! See you in Lund May 12-16! ndpia.se/events/fundame…

Excited to share our latest on the Type II Thoeris system! In collaboration with the Sorek and Kranzusch labs, we identify His-ADPR as a signaling molecule. Huge thanks to all involved—amazing teamwork! nature.com/articles/s4158…

Research from Renee Chang Renee Chang explains how viruses disrupt His-ADPR immune signaling. Kranzusch lab (kranzuschlab.med.harvard.edu), Sorek Lab, Giedre Tamulaitiene, nature nature.com/articles/s4158…

Hidden in plain sight: Bacterial genomes reveal thousands of lytic phages with therapeutic potential biorxiv.org/content/10.110…