BAX and BAK apoptotic pores are different! They release mitochondrial DNA at different speed ⚡️⚡️⚡️ Check out our latest paper in Molecular Cell authors.elsevier.com/sd/article/S10…

Happy to announce that @BBAjournals have made the collection of articles on "Death Mechanisms in Cellular Homeostasis" freely accessible for the next 2 months! Feel free to explore and to RT to your network: sciencedirect.com/journal/biochi… jECS @Eric_Chevet Cristina Muñoz Pinedo - NON professional account @MitosRUs

On #IWD2022, a huge shout out to all those fabulously talented #WomenInSTEM out there, including (but not limited to) all the exceptional female trainees, colleagues, collaborators and supervisors I have worked with over the years! 🎉

The pyroptosis executioner gasdermin D (GSDMD) is a redox sensor. Our new study demonstrates that GSDMD is oxidized to potentiate its oligomerization and pore forming activities, with Cys192 playing a critical role in ROS responsiveness. biorxiv.org/content/10.110…

The case for brakes: Why restrain the size of Bax and Bak pores in outer mitochondrial membranes?: Molecular Cell cell.com/molecular-cell…

Congrats @viten_skap Shirin!!! for winning the poster prize at the #DGfB #biophysics2022 meeting in Konstanz!!!🎉🎉

So honored and humbled to be selected as one of the recipients of the 2022 William B Coley Award, with Judy Lieberman, Feng Shao and Vishva Dixit (Vishva Dixit) for our work on the pore forming proteins gasdermins, cancerresearch.org/news/2022/2022…

Tremendous success: Biologists from Osnabrück University achieve funding by DFG public | @[email protected] for Collaborative Research Center "Functional Plasticity Encoded by Cellular Membrane Networks". "We're delighted," said President Menzel-Riedl & Minister Falko Mohrs. vt.uos.de/9zgnp

#EWCD abstract submission is now open (deadline Feb 3rd, 2023)!!! A great meeting for early career scientists to discuss their latest research in programmed cell death, lysosomal cell death, autophagy, immunology and cancer stem cells. All details at ewcd.eu

Interested to work with a crowd of crazy scientists and support us in admin matters? We hire at the Biocenter, Medical University of Innsbruck. Full time. MS Office, English & German language required. CeMM, @imed_tweets [email protected] for more info, please RT

Great team work Caro Barisch (more active on the blue planet) and @HolthuisL !!!

Our RTG "nanomaterials@biomembranes" made it into the "final 11" - many thanks to the terrific team!

Structural basis of NINJ1-mediated plasma membrane rupture in cell death | Nature nature.com/articles/s4158…

This is pretty incredible. Now, there is a druggable target to delay cell death -or at least, membrane rupture. Potentially useful in settings in which caspase inhibitors did not work, from hepatitis (this paper) to stroke 👏Vishva Dixit and team nature.com/articles/s4158…

Looking for a great conference to end up 2023? Check out our Innate Sensing and Signalling in Immunology meeting (14-15 December 2023, Boston, USA) abcam.com/events/innate-… Organised by myself, Clare Bryant ([email protected]) , JelenaBezbradicaLab , Dr Rebecca Coll and Abcam !

I am amazed by the number of Italians I encountered at #EBSA2023 who are now living abroad. I have a mix of emotions here. I am sad that my homeland is emptying of outstanding scientists, but I am also proud of their courage in pursuing their dreams and embracing new journeys.

First visualization of super-resolved GSDMD pores at the plasma membrane of pyroptotic cells!!! Fantastic work by Shirin @viten_skap and great collaboration with PiehlerLab iBiOs Osnabrück and Hummer Lab Check our preprint! biorxiv.org/content/10.110…

So excited that it's finally out! Congrats 🎉🎉 Eleonora for your great work and all our fantastic collaborators!!! Gasdermin D cysteine residues synergistically control its palmitoylation-mediated membrane targeting and assembly | The EMBO Journal embopress.org/doi/full/10.10…

Very proud of you!!! Congratulations Dr. Kappelhoff 🎉🎉🎉

Here comes our Nature Immunology N&V on a recent nature paper by the Chi lab St. Jude on #mitochondria in the regulation of #IFN signaling in #cancer. Kudos to Katia Cosentino and Joost Verduijn! Ricerca Unimore Fox Chase Cancer Center Available at rdcu.be/emD1n