New >> Last year I wrote about the so-called “gentrification building” TikTok was hating on that was actually affordable housing. Now, the talented @ranjchak has turned my article into an amazing 10 minute YouTube video!

When I visited 3rd and Pine I met an undocumented immigrant struggling to find employment, a woman who survived domestic violence, and a man who has spent half his life selling drugs and merchandise on the sidewalk. These are the people of 3rd and Pine. thestranger.com/slog/2022/03/0…

Have you ever heard of a mysterious region called "killer immunoglobulin-like receptor (KIR)", which is critical for innate #immunity?🧐We analyzed this complex region by deep target sequencing and devising a new #bioinformatics tool Cell Genomics ! cell.com/cell-genomics/…

Episode 40 | Help Is On The Way Mr. President #PensForBiden

A view of today’s afternoon hail storm from west Seattle Seattle Weather Blog

oklama.com

Studying protein without its glycans is like studying a bird without a single feather; even the best-designed and performed study will never see it flying… Our review on developments and perspectives in high-hhroughput glycomics just got published. academic.oup.com/glycob/advance…

Hi Joe President, I have a question

May 5 is a national day of awareness for missing and murdered Indigenous women. For more than a year, reporters across @usatoday network have worked together to examine factors contributing to the crisis and how laws have largely failed to address it.#MMIW usatoday.com/in-depth/news/…

1/6 Can #AlphaFold learn from + & - labeled data to predict peptide binding better? w/ Phil Bradley Justas Dauparas Minkyung Baek Mohamad Abedi David Baker we present joint structure prediction-classification fine-tuning of #AF2 to classify pMHC binding.Institute for Protein Design Fred Hutch Cancer Center

Preprint from Philip Bradley where he creates a version of AlphaFold to model TCR:peptide-MHC interactions. Benchmark is far from perfect, but the paper shows that deep learning-based structural modelling is a possible strategy to predict TCR specificity. doi.org/10.1101/2022.0…

GOODBYE BASEBALL. HELLO POSTSEASON.

BREAKING NEWS: The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”

Our preprint on OpenFold, our trainable reproduction of AlphaFold2, is finally up (biorxiv.org/cgi/content/sh…)! Since we open-sourced parameters in June, we've trained the model to high accuracy more than 50 times, on a variety of datasets. Here's what we learned (a lot) -> (1/19)

A pleasure and a privilege to be assessor again at #CASP15. A mix of spectacular success and the occasional intriguing failure. Looking forward to hearing from the predictors and discussing future directions. Thanks @AJSimpkin Ronan Keegan Shah Mes David L Murphy Filo and Luc.

C-mannosylation of tryptophans is critical for receptor function and trafficking in metazoans, viruses, and malaria parasites. I am thrilled to finally present the structural basis of this mechanistic puzzle! Thank you Ethan Goddard-Borger, Kosslab, Reymond Group! nature.com/articles/s4158…

Statement WWWWWWWin!!

Excited to unveil Boltz-2, our new model capable not only of predicting structures but also binding affinities! Boltz-2 is the first AI model to approach the performance of FEP simulations while being more than 1000x faster! All open-sourced under MIT license! A thread… 🤗🚀